rs2207418
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | ~2x increased risk of heart failure, at least in Amish |
| (C;T) | 1.5 | 1.5x increased risk for heart failure, at least in Amish |
| (T;T) | 0 |
| Reference | GRCh38 38.1/141 |
| Chromosome | 20 |
| Position | 11194255 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2207418 |
| dbSNP (classic) | rs2207418 |
| ClinGen | rs2207418 |
| ebi | rs2207418 |
| HLI | rs2207418 |
| Exac | rs2207418 |
| Gnomad | rs2207418 |
| Varsome | rs2207418 |
| LitVar | rs2207418 |
| Map | rs2207418 |
| PheGenI | rs2207418 |
| Biobank | rs2207418 |
| 1000 genomes | rs2207418 |
| hgdp | rs2207418 |
| ensembl | rs2207418 |
| geneview | rs2207418 |
| scholar | rs2207418 |
| rs2207418 | |
| pharmgkb | rs2207418 |
| gwascentral | rs2207418 |
| openSNP | rs2207418 |
| 23andMe | rs2207418 |
| SNPshot | rs2207418 |
| SNPdbe | rs2207418 |
| MSV3d | rs2207418 |
| GWAS Ctlg | rs2207418 |
| GMAF | 0.3609 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2207418 is a SNP located in a 'gene desert' region of ch 20p12.
In an Amish founder population of 851 individuals, the rs2207418(C) allele was associated with cardiac hypertrophy, increased risk of heart failure (relative risk 1.85, CI: 1.2 - 2.7, p = 0.0019), and increased mortality (hazard risk 1.5, CI: 1.2 - 1.9, p = 0.0004).[PMID 21348951
]
