rs2227589
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 |
| Make rs2227589(A;A) |
| Make rs2227589(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 173917078 |
| Gene | SERPINC1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2227589 |
| dbSNP (classic) | rs2227589 |
| ClinGen | rs2227589 |
| ebi | rs2227589 |
| HLI | rs2227589 |
| Exac | rs2227589 |
| Gnomad | rs2227589 |
| Varsome | rs2227589 |
| LitVar | rs2227589 |
| Map | rs2227589 |
| PheGenI | rs2227589 |
| Biobank | rs2227589 |
| 1000 genomes | rs2227589 |
| hgdp | rs2227589 |
| ensembl | rs2227589 |
| geneview | rs2227589 |
| scholar | rs2227589 |
| rs2227589 | |
| pharmgkb | rs2227589 |
| gwascentral | rs2227589 |
| openSNP | rs2227589 |
| 23andMe | rs2227589 |
| SNPshot | rs2227589 |
| SNPdbe | rs2227589 |
| MSV3d | rs2227589 |
| GWAS Ctlg | rs2227589 |
| GMAF | 0.1253 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
Gene variants associated with deep vein thrombosis.[PMID 18349091]
Updated analysis of gene variants associated with deep vein thrombosis.[PMID 20124536]
rs2227589 in SERPINC1 (risk allele frequency, 0.10) OR 1.29 (95% CI, 1.10-1.49)
[PMID 19229049
] associated with plasma anti-FXa activity and antithrombin levels: carriers of the A allele had slightly but significantly lower anticoagulant activity and levels than GG subjects (97.0+/-7.3% vs. 94.6+/-8.4%; p=0.032; 99.5+/-5.8% vs. 94.8+/-5.6%; p=0.001; respectively)
[PMID 20031567] An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study.
[PMID 21232005] New gene variants associated with venous thrombosis: a replication study in White and Black Americans.
[PMID 23150947] Single nucleotide polymorphisms and the risk of venous thrombosis: results from a Danish case-cohort study
[PMID 23252292] [Correlation of coronary heart disease with multiple genes, gene polymorphisms and multiple risk factors in old Chinese Han patients]
[PMID 23954867] The association of idiopathic recurrent pregnancy loss with polymorphisms in haemostasis-related genes
[PMID 24226152] Influence of single nucleotide polymorphisms on thrombin generation in factor V Leiden heterozygotes
[PMID 25091233] Association of F11 polymorphism rs2289252 with deep vein thrombosis and related phenotypes in population of Latvia
[PMID 25811371] Antithrombin III Deficiency in Indian Patients with Deep Vein Thrombosis: Identification of First India Based AT Variants Including a Novel Point Mutation (T280A) that Leads to Aggregation
