rs2229094
| Orientation | plus |
| Stabilized | plus |
| Make rs2229094(C;C) |
| Make rs2229094(C;T) |
| Make rs2229094(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 31572779 |
| Gene | LOC100287329, LTA |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2229094 |
| dbSNP (classic) | rs2229094 |
| ClinGen | rs2229094 |
| ebi | rs2229094 |
| HLI | rs2229094 |
| Exac | rs2229094 |
| Gnomad | rs2229094 |
| Varsome | rs2229094 |
| LitVar | rs2229094 |
| Map | rs2229094 |
| PheGenI | rs2229094 |
| Biobank | rs2229094 |
| 1000 genomes | rs2229094 |
| hgdp | rs2229094 |
| ensembl | rs2229094 |
| geneview | rs2229094 |
| scholar | rs2229094 |
| rs2229094 | |
| pharmgkb | rs2229094 |
| gwascentral | rs2229094 |
| openSNP | rs2229094 |
| 23andMe | rs2229094 |
| SNPshot | rs2229094 |
| SNPdbe | rs2229094 |
| MSV3d | rs2229094 |
| GWAS Ctlg | rs2229094 |
| GMAF | 0.2677 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
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Associated with at least one "mortality outcome" in a study of ~10,000 individuals.[PMID 18263601]
[PMID 18700950
] 827 males and 709 females, 606 subjects without cancer and 930 subjects with various cancers
- rs2229094(A;A) (T495C, C13R) associated with gastric cancer (TC + CC: TT, adjusted OR = 1.68, 95% CI = 1.06 - 2.65)
in males but not in females
[PMID 20177654] Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians
[PMID 20663564] A Strong Genetic Association between the Tumor Necrosis Factor Locus and Proliferative Vitreoretinopathy: The Retina 4 Project
[PMID 21628868] Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in han chinese
[PMID 16839190] Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.
[PMID 16846490] Lemierre's syndrome and genetic polymorphisms: a case report.
[PMID 17355643] Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.
[PMID 18398712] No association found between the promoter variants of TNF-alpha and diabetic retinopathy in Chinese patients with type 2 diabetes.
[PMID 18598365] Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia.
[PMID 18687755] Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population.
[PMID 18704761] Molecular genetics of myocardial infarction.
[PMID 18715339] Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population.
[PMID 18805939] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
[PMID 19098314] Development of predictive models of proliferative vitreoretinopathy based on genetic variables: the Retina 4 project.
[PMID 20463618] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
[PMID 20811626] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
[PMID 23051989] Investigation of lymphotoxin alpha genetic variants in migraine.
[PMID 28060727] Associations between genetic variants in immunoregulatory genes and risk of non-Hodgkin lymphoma in a Chinese population.
[PMID 32415894] Association of Lymphotoxin-Alpha Gene Polymorphisms (rs909253, rs1800683, and rs2229094) and Risk of Large-Artery Atherosclerosis Stroke in Iranian Population.
[PMID 32420584] The effect of LTA gene polymorphisms on cancer risk: An updated systematic review and meta-analysis.
