rs2241879
| Orientation | minus |
| Stabilized | minus |
| Make rs2241879(C;C) |
| Make rs2241879(C;T) |
| Make rs2241879(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 233274822 |
| Gene | ATG16L1, SCARNA5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2241879 |
| dbSNP (classic) | rs2241879 |
| ClinGen | rs2241879 |
| ebi | rs2241879 |
| HLI | rs2241879 |
| Exac | rs2241879 |
| Gnomad | rs2241879 |
| Varsome | rs2241879 |
| LitVar | rs2241879 |
| Map | rs2241879 |
| PheGenI | rs2241879 |
| Biobank | rs2241879 |
| 1000 genomes | rs2241879 |
| hgdp | rs2241879 |
| ensembl | rs2241879 |
| geneview | rs2241879 |
| scholar | rs2241879 |
| rs2241879 | |
| pharmgkb | rs2241879 |
| gwascentral | rs2241879 |
| openSNP | rs2241879 |
| 23andMe | rs2241879 |
| SNPshot | rs2241879 |
| SNPdbe | rs2241879 |
| MSV3d | rs2241879 |
| GWAS Ctlg | rs2241879 |
| GMAF | 0.3889 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2241879 has been associated with Crohn's disease; the minor allele is somewhat protective in that it lessens the odds of acquiring the disease (odds ratio 0.74, CI: 0.65-0.84, p=3.6x10e-6).[PMID 18162085]
[PMID 21206965] IL23R, NOD2/CARD15, ATG16L1 and PHOX2B polymorphisms in a group of patients with Crohn's disease and correlation with sub-phenotypes
[PMID 21513755] ATG16L1 gene polymorphisms are associated with palmoplantar pustulosis
[PMID 18698678
] Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy.
[PMID 19916168] Genome-wide association studies--a summary for the clinical gastroenterologist.
[PMID 20066736] Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn's disease patients.
[PMID 20082483] NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel disease.
[PMID 20195480] The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.
[PMID 20222171] T300A polymorphism of ATG16L1 and susceptibility to inflammatory bowel diseases: a meta-analysis.
[PMID 20380008] NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease.
[PMID 20454450] Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.
