rs2242446
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in clinvar |
| Make rs2242446(C;T) |
| Make rs2242446(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 55656513 |
| Gene | SLC6A2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2242446 |
| dbSNP (classic) | rs2242446 |
| ClinGen | rs2242446 |
| ebi | rs2242446 |
| HLI | rs2242446 |
| Exac | rs2242446 |
| Gnomad | rs2242446 |
| Varsome | rs2242446 |
| LitVar | rs2242446 |
| Map | rs2242446 |
| PheGenI | rs2242446 |
| Biobank | rs2242446 |
| 1000 genomes | rs2242446 |
| hgdp | rs2242446 |
| ensembl | rs2242446 |
| geneview | rs2242446 |
| scholar | rs2242446 |
| rs2242446 | |
| pharmgkb | rs2242446 |
| gwascentral | rs2242446 |
| openSNP | rs2242446 |
| 23andMe | rs2242446 |
| SNPshot | rs2242446 |
| SNPdbe | rs2242446 |
| MSV3d | rs2242446 |
| GWAS Ctlg | rs2242446 |
| GMAF | 0.2635 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 20863575] Lack of association between response of OROS-methylphenidate and norepinephrine transporter (SLC6A2) polymorphism in Korean ADHD
[PMID 15722184] Norepinephrine transporter (NET) promoter and 5'-UTR polymorphisms: association analysis in panic disorder.
[PMID 17630229] Norepinephrine transporter polymorphisms T-182C and G1287A are not associated with alcohol dependence and its clinical subgroups.
[PMID 18081710
] Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.
[PMID 18779921] The combined effect of norepinephrine transporter gene and negative life events in major depression of Chinese Han population.
[PMID 19693267] Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
[PMID 21412203] Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans.
[PMID 23442739] Psychomotor depressive symptoms may differentially respond to venlafaxine
[PMID 23648227] Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis.
[PMID 25990886] Impact of monoamine-related gene polymorphisms on hippocampal volume in treatment-resistant depression
[PMID 26051731] Association study between 5-HT2A and NET gene polymorphisms and recurrent major depression disorder in Chinese han population
[PMID 26508020] Potential involvement of NET polymorphism in serotonin/norepinephrine reuptake inhibitor response in panic disorder
| ClinVar | |
|---|---|
| Risk | rs2242446(T;T) |
| Alt | rs2242446(T;T) |
| Reference | Rs2242446(C;C) |
| Significance | Probable-non-pathogenic |
| Disease | Orthostatic intolerance |
| Variation | info |
| Gene | SLC6A2 |
| CLNDBN | Orthostatic intolerance |
| Reversed | 0 |
| HGVS | NC_000016.9:g.55690425C>T |
| CLNSRC | |
| CLNACC | RCV000264953.1, |
[PMID 32339102] Age-dependent association of polymorphisms in the promoter and 5'-untranslated region of the norepinephrine transporter gene with generalized anxiety disorder.
[PMID 33340618] Association between genetic variants of the norepinephrine transporter gene (SLC6A2) and bipolar I disorder.
