rs2272383
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal risk | |
| (A;G) | higher body mass index | |
| (G;G) | higher body mass index |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 8101952 |
| Gene | RIC3, TUB |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2272383 |
| dbSNP (classic) | rs2272383 |
| ClinGen | rs2272383 |
| ebi | rs2272383 |
| HLI | rs2272383 |
| Exac | rs2272383 |
| Gnomad | rs2272383 |
| Varsome | rs2272383 |
| LitVar | rs2272383 |
| Map | rs2272383 |
| PheGenI | rs2272383 |
| Biobank | rs2272383 |
| 1000 genomes | rs2272383 |
| hgdp | rs2272383 |
| ensembl | rs2272383 |
| geneview | rs2272383 |
| scholar | rs2272383 |
| rs2272383 | |
| pharmgkb | rs2272383 |
| gwascentral | rs2272383 |
| openSNP | rs2272383 |
| 23andMe | rs2272383 |
| SNPshot | rs2272383 |
| SNPdbe | rs2272383 |
| MSV3d | rs2272383 |
| GWAS Ctlg | rs2272383 |
| GMAF | 0.4394 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs2272383, a SNP in the TUB gene, was found in a study of 492 unrelated type-2 diabetes patients to have a significant effect on body mass index and thus obesity (1.3 kg/m(2), p= 0.01). When two populations were combined, totaling ~1200 patients, the risk allele rs2272383(G) averaged an increase of 0.21 (–0.28 to 0.70).[PMID 16443771]
[PMID 17955208] TUB is a candidate gene for late-onset obesity in women.
[PMID 18183286
] Polymorphisms of the TUB gene are associated with body composition and eating behavior in middle-aged women.
