rs2285053
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;T) | 2 | lower risk (by about 1/2) of lumbar disc disease (based on one 1 Chinese study) |
| (T;T) | 2 | lower risk (by about 1/2) of lumbar disc disease (based on one 1 Chinese study) |
| Make rs2285053(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 55478465 |
| Gene | MMP2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2285053 |
| dbSNP (classic) | rs2285053 |
| ClinGen | rs2285053 |
| ebi | rs2285053 |
| HLI | rs2285053 |
| Exac | rs2285053 |
| Gnomad | rs2285053 |
| Varsome | rs2285053 |
| LitVar | rs2285053 |
| Map | rs2285053 |
| PheGenI | rs2285053 |
| Biobank | rs2285053 |
| 1000 genomes | rs2285053 |
| hgdp | rs2285053 |
| ensembl | rs2285053 |
| geneview | rs2285053 |
| scholar | rs2285053 |
| rs2285053 | |
| pharmgkb | rs2285053 |
| gwascentral | rs2285053 |
| openSNP | rs2285053 |
| 23andMe | rs2285053 |
| SNPshot | rs2285053 |
| SNPdbe | rs2285053 |
| MSV3d | rs2285053 |
| GWAS Ctlg | rs2285053 |
| GMAF | 0.1726 |
| Max Magnitude | 2 |
rs2285053, also known as -735C>T, represents a variant in the promoter of the MMP2 gene on chromosome 16.
A study of ~1000 Han Chinese patients with lumbar disc disease concluded that rs2285053(T) carriers were at lower risk for the disorder.[PMID 23852912
]
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