| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
common in complete genomics
|
Although an initial report in 2005 found an association between the minor allele of rs2313982 and Parkinson's disease, subsequent reports have not found any statistically significant association, most notably a meta-analysis totaling over 3,000 patients published in 2010.
| Rs2313982
|
| PubMed
|
[PMID 16252231 ]
|
| Affy Probeset
|
SNP_A-4264503
|
| Affy Orientation
|
same
|
| On GW 5.0
|
|
| Alleles A/B
|
C/T
|
| Ancestral
|
|
| Population
|
|
| Allele
|
T
|
| Case Freq.
|
0.12
|
| Control Freq.
|
0.06
|
| Odds Ratio Het
|
|
| Odds Ratio Hom
|
|
| Odds Ratio All
|
2.01
|
| Disease
|
Parkinson's disease (PKD)
|
[PMID 16685661] Genomewide association, Parkinson disease, and PARK10.
[PMID 16685662] No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.
[PMID 16685663] A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan.
[PMID 17332845] Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease.
[PMID 19475631] Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study.
]
