rs2523608

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar

Make rs2523608(C;T)

Make rs2523608(T;T)

Reference

GRCh38 38.1/141

Chromosome

6

Position

31354782

Gene	HLA-B, MIR6891

is a	snp
is	mentioned by
dbSNP	rs2523608
dbSNP (classic)	rs2523608
ClinGen	rs2523608
ebi	rs2523608
HLI	rs2523608
Exac	rs2523608
Gnomad	rs2523608
Varsome	rs2523608
LitVar	rs2523608
Map	rs2523608
PheGenI	rs2523608
Biobank	rs2523608
1000 genomes	rs2523608
hgdp	rs2523608
ensembl	rs2523608
geneview	rs2523608
scholar	rs2523608
google	rs2523608
pharmgkb	rs2523608
gwascentral	rs2523608
openSNP	rs2523608
23andMe	rs2523608
SNPshot	rs2523608
SNPdbe	rs2523608
MSV3d	rs2523608
GWAS Ctlg	rs2523608

GMAF

0.421

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 20205591]
Trait	HIV-1 control
Title	Host determinants of HIV-1 control in African Americans
Risk Allele
P-val	0.000003
Odds Ratio	None None

GWAS snp
PMID	[PMID 21051598]
Trait
Title	The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation
Risk Allele	G
P-val	9E-20
Odds Ratio	2.6000 [NR]

ClinVar
Risk	rs2523608(T;T)
Alt	rs2523608(T;T)
Reference	Rs2523608(C;C)
Significance	Histocompatibility
Disease
Variation	info
Gene	HLA-B
CLNDBN
Reversed	1
HGVS	NC_000006.11:g.31322559G>A
CLNSRC
CLNACC

[PMID 20018067] A two-stage search strategy for detecting multiple loci associated with rheumatoid arthritis.

[PMID 22474614] Host Genes Important to HIV Replication and Evolution.

GWAS snp
PMID	[PMID 23417110]
Trait	Beta-2 microglubulin plasma levels
Title	Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.
Risk Allele	A
P-val	9E-9
Odds Ratio	.02 [0.012-0.028] unit increase