rs2572886
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2.1 | 1.4x increased risk of HIV infection |
| (A;G) | 2 | 1.4x increased risk of HIV infection |
| (G;G) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 142821739 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2572886 |
| dbSNP (classic) | rs2572886 |
| ClinGen | rs2572886 |
| ebi | rs2572886 |
| HLI | rs2572886 |
| Exac | rs2572886 |
| Gnomad | rs2572886 |
| Varsome | rs2572886 |
| LitVar | rs2572886 |
| Map | rs2572886 |
| PheGenI | rs2572886 |
| Biobank | rs2572886 |
| 1000 genomes | rs2572886 |
| hgdp | rs2572886 |
| ensembl | rs2572886 |
| geneview | rs2572886 |
| scholar | rs2572886 |
| rs2572886 | |
| pharmgkb | rs2572886 |
| gwascentral | rs2572886 |
| openSNP | rs2572886 |
| 23andMe | rs2572886 |
| SNPshot | rs2572886 |
| SNPdbe | rs2572886 |
| MSV3d | rs2572886 |
| GWAS Ctlg | rs2572886 |
| GMAF | 0.1446 |
| Max Magnitude | 2.1 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs2572886 is a SNP determined by both linkage studies and in-vitro experiments to increase the susceptibility to infection by HIV. The risk allele, rs2572886(A), yields an odds ratio of 1.4 (p=0.001), and also appears to be associated with higher viral load and faster disease progression.
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[PMID 18288889
]
[PMID 21221856] The search for host genetic factors of HIV/AIDS pathogenesis in the post-genome era: progress to date and new avenues for discovery.
