rs2606345
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| Make rs2606345(A;A) |
| Make rs2606345(A;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 74724835 |
| Gene | CYP1A1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2606345 |
| dbSNP (classic) | rs2606345 |
| ClinGen | rs2606345 |
| ebi | rs2606345 |
| HLI | rs2606345 |
| Exac | rs2606345 |
| Gnomad | rs2606345 |
| Varsome | rs2606345 |
| LitVar | rs2606345 |
| Map | rs2606345 |
| PheGenI | rs2606345 |
| Biobank | rs2606345 |
| 1000 genomes | rs2606345 |
| hgdp | rs2606345 |
| ensembl | rs2606345 |
| geneview | rs2606345 |
| scholar | rs2606345 |
| rs2606345 | |
| pharmgkb | rs2606345 |
| gwascentral | rs2606345 |
| openSNP | rs2606345 |
| 23andMe | rs2606345 |
| SNPshot | rs2606345 |
| SNPdbe | rs2606345 |
| MSV3d | rs2606345 |
| GWAS Ctlg | rs2606345 |
| GMAF | 0.3352 |
| Max Magnitude | 0 |
[PMID 18415690] 577 testicular germ cell tumors cases (254 seminoma, 323 nonseminoma) and 707 controls.
inversely associated with nonseminoma:
- rs4886605 OR = 0.75 (95% CI = 0.54-1.04) among the heterozygotes and OR = 0.37, 95% CI = 0.12-1.11 among the homozygotes with a p-value for trend = 0.02;
- rs2606345 OR = 0.69 (95% CI = 0.51-0.93) among heterozygotes and OR = 0.70 (95% CI = 0.42-1.17) among homozygotes, with a p-value for trend = 0.02.
[PMID 19168589
] Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China
[PMID 19479063] Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression
[PMID 19630952] Sex steroid metabolism polymorphisms and mammographic density in pre- and early peri-menopausal women
[PMID 16949383] Sex steroid hormone pathway genes and health-related measures in women of 4 races/ethnicities: the Study of Women's Health Across the Nation (SWAN).
[PMID 16949388] CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal.
[PMID 16949389] Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptors.
[PMID 16949393] Sex steroid hormone gene polymorphisms and depressive symptoms in women at midlife.
[PMID 18268125] Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.
[PMID 18579753] Vascular actions of estrogens: functional implications.
[PMID 18632753] Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
[PMID 18691756] Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk.
[PMID 18936436] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.
[PMID 19330903] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
[PMID 22569204] PharmGKB summary: phenytoin pathway.
[PMID 23411129] Functional polymorphisms in the CYP1A1, ACE, and IL-6 genes contribute to susceptibility to community-acquired and nosocomial pneumonia
[PMID 23107763] Host genetic risk factors for community-acquired pneumonia.
[PMID 23661361] The potential effect of gender in CYP1A1 and GSTM1 genotype-specific associations with pediatric brain tumor.
[PMID 24068433] CYP1A1, GCLC, AGT, AGTR1 gene-gene interactions in community-acquired pneumonia pulmonary complications
[PMID 28403117] Association of the ACE, GSTM1, IL-6, NOS3, and CYP1A1 polymorphisms with susceptibility of mycoplasma pneumoniae pneumonia in Chinese children.
