rs2609653
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | |
| (C;C) | 3.6x risk | |
| (C;T) | 1.5x risk | |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 34379474 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2609653 |
| dbSNP (classic) | rs2609653 |
| ClinGen | rs2609653 |
| ebi | rs2609653 |
| HLI | rs2609653 |
| Exac | rs2609653 |
| Gnomad | rs2609653 |
| Varsome | rs2609653 |
| LitVar | rs2609653 |
| Map | rs2609653 |
| PheGenI | rs2609653 |
| Biobank | rs2609653 |
| 1000 genomes | rs2609653 |
| hgdp | rs2609653 |
| ensembl | rs2609653 |
| geneview | rs2609653 |
| scholar | rs2609653 |
| rs2609653 | |
| pharmgkb | rs2609653 |
| gwascentral | rs2609653 |
| openSNP | rs2609653 |
| 23andMe | rs2609653 |
| SNPshot | rs2609653 |
| SNPdbe | rs2609653 |
| MSV3d | rs2609653 |
| GWAS Ctlg | rs2609653 |
| GMAF | 0.05418 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2609653 has been reported in a large study to be associated with bipolar disorder.
The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.43 (CI 1.19-1.71), and for homozygotes, 3.62 (CI 1.26-10.44). [PMID 17554300
]
| GWAS snp | |
|---|---|
| PMID | [PMID 21254220 |
| Trait | |
| Title | Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder. |
| Risk Allele | |
| P-val | 0.000007 |
| Odds Ratio | None None |
| GWAS snp | |
|---|---|
| PMID | [PMID 23453885 |
| Trait | Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) |
| Title | Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. |
| Risk Allele | T |
| P-val | 3E-6 |
| Odds Ratio | 1.13 [1.07-1.19] |
