rs261332

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	2	associated with higher HDL cholesterol
(A;G)	2	associated with higher HDL cholesterol
(G;G)	0	common in complete genomics

Reference

GRCh38 38.1/141

Chromosome

15

Position

58435126

Gene	LIPC, LIPC-AS1

is a	snp
is	mentioned by
dbSNP	rs261332
dbSNP (classic)	rs261332
ClinGen	rs261332
ebi	rs261332
HLI	rs261332
Exac	rs261332
Gnomad	rs261332
Varsome	rs261332
LitVar	rs261332
Map	rs261332
PheGenI	rs261332
Biobank	rs261332
1000 genomes	rs261332
hgdp	rs261332
ensembl	rs261332
geneview	rs261332
scholar	rs261332
google	rs261332
pharmgkb	rs261332
gwascentral	rs261332
openSNP	rs261332
23andMe	rs261332
SNPshot	rs261332
SNPdbe	rs261332
MSV3d	rs261332
GWAS Ctlg	rs261332

GMAF

0.1924

Max Magnitude

2

?	(A;A) (A;G) (G;G)	28

Rs261332
PubMed	[PMID 17463246]
Affy Probeset	SNP_A-4301630
Affy Orientation	reverse
On GW 5.0	1
Alleles A/B	C/T
Ancestral
Population	NEU
Allele	A
Case Freq.
Control Freq.	0.18
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All	-
Disease	Elevated HDL-Cholesterol (E-HDL)

rs261332 increases susceptibility to Elevated HDL-Cholesterol for carriers of the A allele [PMID 17463246]

A allele is associated with 1.41mg/dl increase in HDL cholesterol (good cholesterol). [PMID 18193043]

[PMID 18179892] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.

[PMID 19101670] LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.

[PMID 21283740] Large-scale candidate gene analysis of HDL particle features.