rs2884737
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs2884737(A;C) |
| Make rs2884737(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 31094233 |
| Gene | VKORC1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2884737 |
| dbSNP (classic) | rs2884737 |
| ClinGen | rs2884737 |
| ebi | rs2884737 |
| HLI | rs2884737 |
| Exac | rs2884737 |
| Gnomad | rs2884737 |
| Varsome | rs2884737 |
| LitVar | rs2884737 |
| Map | rs2884737 |
| PheGenI | rs2884737 |
| Biobank | rs2884737 |
| 1000 genomes | rs2884737 |
| hgdp | rs2884737 |
| ensembl | rs2884737 |
| geneview | rs2884737 |
| scholar | rs2884737 |
| rs2884737 | |
| pharmgkb | rs2884737 |
| gwascentral | rs2884737 |
| openSNP | rs2884737 |
| 23andMe | rs2884737 |
| SNPshot | rs2884737 |
| SNPdbe | rs2884737 |
| MSV3d | rs2884737 |
| GWAS Ctlg | rs2884737 |
| GMAF | 0.129 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 21179439
] VKORC1 common variation and bone mineral density in the Third National Health and Nutrition Examination Survey
[PMID 18305455] Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.
[PMID 18855533] VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.
[PMID 19074728] Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy.
[PMID 19228618] Estimation of the warfarin dose with clinical and pharmacogenetic data.
[PMID 19436136] Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status.
[PMID 20585445] A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants.
[PMID 21359226] The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected.
[PMID 23662025] Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population
[PMID 23133420] Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.
| ClinVar | |
|---|---|
| Risk | rs2884737(C;C) |
| Alt | rs2884737(C;C) |
| Reference | Rs2884737(A;A) |
| Significance | Drug-response |
| Disease | warfarin response - Dosage |
| Variation | info |
| Gene | VKORC1 |
| CLNDBN | warfarin response - Dosage |
| Reversed | 0 |
| HGVS | NC_000016.9:g.31105554A>C |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211273.1, |
