rs2891168
| Orientation | plus |
| Stabilized | plus |
| Make rs2891168(A;A) |
| Make rs2891168(A;G) |
| Make rs2891168(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 22098620 |
| Gene | CDKN2B-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2891168 |
| dbSNP (classic) | rs2891168 |
| ClinGen | rs2891168 |
| ebi | rs2891168 |
| HLI | rs2891168 |
| Exac | rs2891168 |
| Gnomad | rs2891168 |
| Varsome | rs2891168 |
| LitVar | rs2891168 |
| Map | rs2891168 |
| PheGenI | rs2891168 |
| Biobank | rs2891168 |
| 1000 genomes | rs2891168 |
| hgdp | rs2891168 |
| ensembl | rs2891168 |
| geneview | rs2891168 |
| scholar | rs2891168 |
| rs2891168 | |
| pharmgkb | rs2891168 |
| gwascentral | rs2891168 |
| openSNP | rs2891168 |
| 23andMe | rs2891168 |
| SNPshot | rs2891168 |
| SNPdbe | rs2891168 |
| MSV3d | rs2891168 |
| GWAS Ctlg | rs2891168 |
| GMAF | 0.4201 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| Rs2891168 | |
|---|---|
| PubMed | [PMID 17478681 ]
|
| Affy Probeset | SNP_A-2150146 |
| Affy Orientation | same |
| On GW 5.0 | 1 |
| Alleles A/B | A/G |
| Ancestral | A |
| Population | CEU |
| Allele | G |
| Case Freq. | |
| Control Freq. | |
| Odds Ratio Het | 1.30 |
| Odds Ratio Hom | 1.54 |
| Odds Ratio All | 1.23 |
| Disease | Coronary artery disease (CAD) |
rs2891168 increases susceptibility to Coronary artery disease 1.30 times for heterozygotes (AG) and 1.54 times for homozygotes (GG) [PMID 18048406]
[PMID 19463184] Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease
[PMID 20696043] Replication of the association of chromosomal region 9p21.3 with generalized aggressive periodontitis (gAgP) using an independent case-control cohort
[PMID 21949331] 44 Tiling array shows low ANRIL, high CDKN2B expression associated with chromosome 9p21 coronary artery disease (CAD) risk genotype
[PMID 18987759] Genetic testing for atherosclerosis risk: inevitability or pipe dream?
[PMID 19019192] Association of genetic variation on chromosome 9p21.3 and arterial stiffness.
[PMID 19214202] Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.
[PMID 19578366] Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
[PMID 19888323] Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
[PMID 20403154] Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population.
