rs2976392
| Orientation | plus |
| Stabilized | plus |
| Make rs2976392(A;A) |
| Make rs2976392(A;G) |
| Make rs2976392(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 142681514 |
| Gene | PSCA |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2976392 |
| dbSNP (classic) | rs2976392 |
| ClinGen | rs2976392 |
| ebi | rs2976392 |
| HLI | rs2976392 |
| Exac | rs2976392 |
| Gnomad | rs2976392 |
| Varsome | rs2976392 |
| LitVar | rs2976392 |
| Map | rs2976392 |
| PheGenI | rs2976392 |
| Biobank | rs2976392 |
| 1000 genomes | rs2976392 |
| hgdp | rs2976392 |
| ensembl | rs2976392 |
| geneview | rs2976392 |
| scholar | rs2976392 |
| rs2976392 | |
| pharmgkb | rs2976392 |
| gwascentral | rs2976392 |
| openSNP | rs2976392 |
| 23andMe | rs2976392 |
| SNPshot | rs2976392 |
| SNPdbe | rs2976392 |
| MSV3d | rs2976392 |
| GWAS Ctlg | rs2976392 |
| GMAF | 0.4311 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 18488030] rs2976392 and diffuse-type gastric cancer (allele-specific odds ratio (OR) = 1.62, 95% CI = 1.38-1.89, P = 1.11 x 10(-9)). Substitution of the C allele with the risk allele T at a SNP in the first exon (rs2294008, which has r(2) = 0.995, D' = 0.999 with rs2976392) reduces transcriptional activity of an upstream fragment of the gene
[PMID 20131315] Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-gastric cancer in a Chinese population
[PMID 22481254] The PSCA polymorphisms derived from genome-wide association study are associated with risk of gastric cancer: a meta-analysis
[PMID 19554573] Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population.
[PMID 19582881] Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese.
[PMID 22037551] A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.
[PMID 22426141] Prostate stem cell antigen polymorphisms and susceptibility to gastric cancer: a systematic review and meta-analysis.
[PMID 25503145] PSCA and MUC1 Gene Polymorphisms Are Linked with Gastric Cancer and Pre-malignant Gastric Conditions
[PMID 26006239
] The Influence of PSCA Gene Variation on Its Expression and Gastric Adenocarcinoma Susceptibility in the Northwest Chinese Population
[PMID 26320491] Common Genetic Variants of PSCA, MUC1 and PLCE1 Genes are not Associated with Colorectal Cancer
[PMID 26848528] PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population.
[PMID 26891331] Impact of DCC (rs714) and PSCA (rs2294008 and rs2976392) Gene Polymorphism in Modulating Cancer Risk in Asian Population.
[PMID 31983162] Association between PSCA, TNF-α, PARP1 and TP53 Gene Polymorphisms and Gastric Cancer Susceptibility in the Brazilian Population.
