rs3135388(T;T)
From SNPedia
3-6x higher risk of multiple sclerosis |
Is a | genotype |
of | rs3135388 |
Gene | HLA-DRA |
Chromosome | 6 |
Position | 32,445,274 |
mentioned | by |
Magnitude | 2 |
Repute | Bad |
Geno | Mag | Summary |
---|---|---|
(C;C) | 0 | normal |
(C;T) | 1.8 | 3x higher risk of multiple sclerosis |
(T;T) | 2 | 3-6x higher risk of multiple sclerosis |
Rs3135388(T;T) is highly correlated with the HLA-DRB1*1501 allele. There is 3-6x higher risk of multiple sclerosis associated with the (T;T) genotype.