rs3135391(T;T)
From SNPedia
3 to 6 fold higher risk for multiple sclerosis |
Is a | genotype |
of | rs3135391 |
Gene | HLA-DRA |
Chromosome | 6 |
Position | 32,443,210 |
mentioned | by |
Magnitude | 3 |
Repute | Bad |
Geno | Mag | Summary |
---|---|---|
(C;C) | 0 | normal |
(C;T) | 2 | HLA-DRB1*1501 carrier; higher multiple sclerosis risk |
(T;T) | 3 | 3 to 6 fold higher risk for multiple sclerosis |
Rs3135391(T;T) is highly correlated with the HLA-DRB1*1501 allele. There is 3-6x higher risk of multiple sclerosis associated with the (T;T) genotype.