rs3217992

minus

Geno	Mag	Summary
(A;A)		1.24x increased myocardial infarction risk
(A;G)		1.24x increased myocardial infarction risk
(G;G)		normal

Reference

GRCh38 38.1/141

Chromosome

9

Position

22003224

Gene	CDKN2B, CDKN2B-AS1

is a	snp
is	mentioned by
dbSNP	rs3217992
dbSNP (classic)	rs3217992
ClinGen	rs3217992
ebi	rs3217992
HLI	rs3217992
Exac	rs3217992
Gnomad	rs3217992
Varsome	rs3217992
LitVar	rs3217992
Map	rs3217992
PheGenI	rs3217992
Biobank	rs3217992
1000 genomes	rs3217992
hgdp	rs3217992
ensembl	rs3217992
geneview	rs3217992
scholar	rs3217992
google	rs3217992
pharmgkb	rs3217992
gwascentral	rs3217992
openSNP	rs3217992
23andMe	rs3217992
SNPshot	rs3217992
SNPdbe	rs3217992
MSV3d	rs3217992
GWAS Ctlg	rs3217992

GMAF

0.3595

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

[PMID 25814643 ] Genetic Variations in MicroRNA-Binding Sites Affect MicroRNA-Mediated Regulation of Several Genes Associated With Cardio-metabolic Phenotypes

rs3217992 is a SNP in the cyclin-dependent kinase inhibitor 2B CDKN2B gene. A study of 432 Han Chinese patients with myocardial infarctions concluded that male subjects carrying a rs3217992(A) allele were at 1.24x increased risk (for MI).[PMID 19272367]

[PMID 23202125 ] Large-scale association analysis identifies new risk loci for coronary artery disease.

[PMID 23111177 ] CDKN2B-AS1 Genotype-Glaucoma Feature Correlations in Primary Open-Angle Glaucoma Patients From the United States

[PMID 20386740 ] Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.

[PMID 20978019] CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection

[PMID 19559344] Genetic variants on chromosome 9p21 and ischemic stroke in Chinese

[PMID 19258477 ] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

[PMID 18174243 ] Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

[PMID 17459456 ] A common variant of the p16(INK4a) genetic region is associated with physical function in older people.

[PMID 27486979 ] Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk.

[PMID 29228923 ] CDKN2BAS gene polymorphisms and the risk of intracranial aneurysm in the Chinese population.

[PMID 30774116 ] Functional Genetic Single-Nucleotide Polymorphisms (SNPs) in Cyclin-Dependent Kinase Inhibitor 2A/B (CDKN2A/B) Locus Are Associated with Risk and Prognosis of Osteosarcoma in Chinese Populations.

[PMID 31770616] ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD.