rs3218005
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common/normal |
| (A;G) | ? | |
| (G;G) | 1.5 | Slightly higher (1.55x) risk for breast cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 22000248 |
| Gene | CDKN2B-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3218005 |
| dbSNP (classic) | rs3218005 |
| ClinGen | rs3218005 |
| ebi | rs3218005 |
| HLI | rs3218005 |
| Exac | rs3218005 |
| Gnomad | rs3218005 |
| Varsome | rs3218005 |
| LitVar | rs3218005 |
| Map | rs3218005 |
| PheGenI | rs3218005 |
| Biobank | rs3218005 |
| 1000 genomes | rs3218005 |
| hgdp | rs3218005 |
| ensembl | rs3218005 |
| geneview | rs3218005 |
| scholar | rs3218005 |
| rs3218005 | |
| pharmgkb | rs3218005 |
| gwascentral | rs3218005 |
| openSNP | rs3218005 |
| 23andMe | rs3218005 |
| SNPshot | rs3218005 |
| SNPdbe | rs3218005 |
| MSV3d | rs3218005 |
| GWAS Ctlg | rs3218005 |
| GMAF | 0.1579 |
| Max Magnitude | 1.5 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs3218005 shows an association with breast cancer in a British study involving ~2300 patients. The odds ratio for the (G;G) vs (A;A) homozygotes is 1.55 (CI: 1.02-2.37, p=0.013).[PMID 18174243
]
[PMID 17459456] A common variant of the p16(INK4a) genetic region is associated with physical function in older people.
[PMID 19258477] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
[PMID 20386740] Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.
