| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
common on affy axiom data
|
| (C;T)
|
1.6
|
1.6x increase in risk for psoriatic arthritis
|
| (T;T)
|
2
|
1.6x increase in risk for psoriatic arthritis
|
[PMID 25651891
] reports rs33980500, with risk/non-risk alleles T/C, has an odds ratio of 1.6 (p=2.65e−16) for psoriatic arthritis based on a case/control study of ~2,000 patients.
[PMID 20953186] Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
| GWAS snp
|
| PMID
|
[PMID 20953188]
|
| Trait
|
|
| Title
|
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
|
| Risk Allele
|
T
|
| P-val
|
1E-16
|
| Odds Ratio
|
None None
|
[PMID 22513239] Identification of low frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization
[PMID 22445837] TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in Inflammatory Bowel Disease.
[PMID 23116200] New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis
[PMID 24005976] Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk
[PMID 23836313] TRAF3IP2 gene and systemic lupus erythematosus: association with disease susceptibility and pericarditis development.
[PMID 29302052] The Act1 D10N missense variant impairs CD40 signaling in human B-cells.
] reports rs33980500, with risk/non-risk alleles T/C, has an odds ratio of 1.6 (p=2.65e−16) for psoriatic arthritis based on a case/control study of ~2,000 patients.
