Geno
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Mag
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Summary
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(C;C)
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0
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common in complete genomics
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[PMID 20386561] Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
[PMID 21903774] A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients
[PMID 21902502] Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors dose requirements and trough blood levels in stable renal transplant patients
[PMID 21946898] Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study.
[PMID 22388796] The new CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney transplant patients.
[PMID 23252948] CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy
[PMID 23574377] Severe acute nephrotoxicity in a kidney transplant patient despite low tacrolimus levels: a possible interaction between donor and recipient genetic polymorphisms
[PMID 23501331] Effects of atorvastatin on CYP3A4 and CYP3A5 mRNA expression in mononuclear cells and CYP3A activity in hypercholeresterolemic patients.
[PMID 26488616] CYP3A4 intronic SNP rs35599367 (CYP3A4*22) alters RNA splicing