rs3745367
| Orientation | plus |
| Stabilized | plus |
| Make rs3745367(A;A) |
| Make rs3745367(A;G) |
| Make rs3745367(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 7669625 |
| Gene | RETN |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3745367 |
| dbSNP (classic) | rs3745367 |
| ClinGen | rs3745367 |
| ebi | rs3745367 |
| HLI | rs3745367 |
| Exac | rs3745367 |
| Gnomad | rs3745367 |
| Varsome | rs3745367 |
| LitVar | rs3745367 |
| Map | rs3745367 |
| PheGenI | rs3745367 |
| Biobank | rs3745367 |
| 1000 genomes | rs3745367 |
| hgdp | rs3745367 |
| ensembl | rs3745367 |
| geneview | rs3745367 |
| scholar | rs3745367 |
| rs3745367 | |
| pharmgkb | rs3745367 |
| gwascentral | rs3745367 |
| openSNP | rs3745367 |
| 23andMe | rs3745367 |
| SNPshot | rs3745367 |
| SNPdbe | rs3745367 |
| MSV3d | rs3745367 |
| GWAS Ctlg | rs3745367 |
| GMAF | 0.3848 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 20300528
] A at single nucleotide polymorphism-358 is required for g at -420 to confer the highest plasma resistin in the general Japanese population
[PMID 15338456] The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.
[PMID 15517149] Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.
[PMID 16670163] Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians.
[PMID 18239575] Analysis of genetic variations in the resistin gene shows no associations with obesity in women.
[PMID 19074981] Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study.
| GWAS snp | |
|---|---|
| PMID | [PMID 22843503]
|
| Trait | Resistin levels |
| Title | Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. |
| Risk Allele | A |
| P-val | 3E-6 |
| Odds Ratio | .04 [0.020-0.060] unit increase |
[PMID 24123702] Common quantitative trait locus downstream of RETN gene identified by genome-wide association study is associated with risk of type 2 diabetes mellitus in Han Chinese: A Mendelian randomization effect
[PMID 23203410] Resistin polymorphisms show associations with obesity, but not with bone parameters in men: results from the Odense Androgen Study.
[PMID 25811207] Polymorphisms in RETN gene and susceptibility to colon cancer in Saudi patients
[PMID 27159547] Adipokine Gene Single-Nucleotide Polymorphisms in Portuguese Obese Adolescents: Associations with Plasma Concentrations of Adiponectin, Resistin, IL-6, IL-1β, and TNF-α.
[PMID 27699082] Relevance Study on Cerebral Infarction and Resistin Gene Polymorphism in Chinese Han Population.
[PMID 29384942] Correlation between resistin gene polymorphism and clinical aspects of lung cancer.
[PMID 29561430] Resistin polymorphisms are associated with rheumatoid arthritis susceptibility in Chinese Han subjects.
[PMID 32112497] Resistin adipokin in atopic dermatitis patients: A clinical, biochemical, and genetic study.
[PMID 32226495] Impacts of RETN genetic polymorphism on breast cancer development.
[PMID 33269434] Association of resistin (rs3745367) and urotensin II (rs228648 and rs2890565) gene polymorphisms with risk of type 2 diabetes mellitus in Indian population.
