rs3747742
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 2 |
| Make rs3747742(C;C) |
| Make rs3747742(C;T) |
| Make rs3747742(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 41194780 |
| Gene | TREML2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3747742 |
| dbSNP (classic) | rs3747742 |
| ClinGen | rs3747742 |
| ebi | rs3747742 |
| HLI | rs3747742 |
| Exac | rs3747742 |
| Gnomad | rs3747742 |
| Varsome | rs3747742 |
| LitVar | rs3747742 |
| Map | rs3747742 |
| PheGenI | rs3747742 |
| Biobank | rs3747742 |
| 1000 genomes | rs3747742 |
| hgdp | rs3747742 |
| ensembl | rs3747742 |
| geneview | rs3747742 |
| scholar | rs3747742 |
| rs3747742 | |
| pharmgkb | rs3747742 |
| gwascentral | rs3747742 |
| openSNP | rs3747742 |
| 23andMe | rs3747742 |
| SNPshot | rs3747742 |
| SNPdbe | rs3747742 |
| MSV3d | rs3747742 |
| GWAS Ctlg | rs3747742 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3747742 is a SNP in the Triggering receptor expressed on myeloid cells-like 2 TREML2 gene.
See the genotype page rs3747742(G;G).
The minor allele of rs3747742 has been reported in a large study (IGAP) to be associated with a reduced risk of Alzheimer's Disease. The protective allele is (G). The odds ratio associated with heterozygotes and homozygotes of the G allele versus the A allele is 0.93 (CI 0.89-0.96).
[PMID 24439484
] Missense variant in TREML2 protects against Alzheimer's disease
