rs3761863
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs3761863(A;G) |
| Make rs3761863(G;G) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 12 |
| Position | 40364850 |
| Gene | LOC105369736, LRRK2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3761863 |
| dbSNP (classic) | rs3761863 |
| ClinGen | rs3761863 |
| ebi | rs3761863 |
| HLI | rs3761863 |
| Exac | rs3761863 |
| Gnomad | rs3761863 |
| Varsome | rs3761863 |
| LitVar | rs3761863 |
| Map | rs3761863 |
| PheGenI | rs3761863 |
| Biobank | rs3761863 |
| 1000 genomes | rs3761863 |
| hgdp | rs3761863 |
| ensembl | rs3761863 |
| geneview | rs3761863 |
| scholar | rs3761863 |
| rs3761863 | |
| pharmgkb | rs3761863 |
| gwascentral | rs3761863 |
| openSNP | rs3761863 |
| 23andMe | rs3761863 |
| SNPshot | rs3761863 |
| SNPdbe | rs3761863 |
| MSV3d | rs3761863 |
| GWAS Ctlg | rs3761863 |
| GMAF | 0.4495 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 23967090
] Fine-Mapping, Gene Expression and Splicing Analysis of the Disease Associated LRRK2 Locus
| ClinVar | |
|---|---|
| Risk | rs3761863(G;G) |
| Alt | rs3761863(G;G) |
| Reference | Rs3761863(A;A) |
| Significance | Non-pathogenic |
| Disease | Parkinson disease 8 |
| Variation | info |
| Gene | LRRK2 |
| CLNDBN | Parkinson disease 8, autosomal dominant |
| Reversed | 1 |
| HGVS | NC_000012.11:g.40758652T\x3d; NC_000012.11:g.40758652T>C |
| CLNSRC | ClinVar GeneReviews |
| CLNACC | RCV000032513.1, RCV000375193.1, |
[PMID 16960813] LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago.
[PMID 17614198] Lrrk2 mutations in South America: A study of Chilean Parkinson's disease.
[PMID 18952485] Haplotype analysis of Lrrk2 R1441H carriers with parkinsonism.
[PMID 26844546] A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.
