| Rs3765598
|
| PubMed
|
[PMID 16175503 ]
|
| Affy Probeset
|
SNP_A-1962697
|
| Affy Orientation
|
same
|
| On GW 5.0
|
1
|
| Alleles A/B
|
C/T
|
| Ancestral
|
C
|
| Population
|
Caucasian
|
| Allele
|
T
|
| Case Freq.
|
0.21
|
| Control Freq.
|
0.16
|
| Odds Ratio Het
|
|
| Odds Ratio Hom
|
|
| Odds Ratio All
|
1.40
|
| Disease
|
Rheumatoid Arthritis (RA)
|
rs3765598 is in linkage disequilibrium with a polymorphism that increases susceptibility to Rheumatoid Arthritis 1.40 times for carriers of the T allele [PMID 16175503]
[PMID 19180477] Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.
[PMID 19956096] rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 23950893] PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes
]
