rs3790567
| Orientation | plus |
| Stabilized | plus |
| Make rs3790567(A;A) |
| Make rs3790567(A;G) |
| Make rs3790567(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 67356694 |
| Gene | IL12RB2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3790567 |
| dbSNP (classic) | rs3790567 |
| ClinGen | rs3790567 |
| ebi | rs3790567 |
| HLI | rs3790567 |
| Exac | rs3790567 |
| Gnomad | rs3790567 |
| Varsome | rs3790567 |
| LitVar | rs3790567 |
| Map | rs3790567 |
| PheGenI | rs3790567 |
| Biobank | rs3790567 |
| 1000 genomes | rs3790567 |
| hgdp | rs3790567 |
| ensembl | rs3790567 |
| geneview | rs3790567 |
| scholar | rs3790567 |
| rs3790567 | |
| pharmgkb | rs3790567 |
| gwascentral | rs3790567 |
| openSNP | rs3790567 |
| 23andMe | rs3790567 |
| SNPshot | rs3790567 |
| SNPdbe | rs3790567 |
| MSV3d | rs3790567 |
| GWAS Ctlg | rs3790567 |
| GMAF | 0.3604 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
- Each G at rs2856683 increased the odds of primary biliary cirrhosis by 1.75x.
- Each G at rs6441286 increased the odds of primary biliary cirrhosis by 1.54x.
- Each A at rs3790567 increased the odds of primary biliary cirrhosis by 1.51x.
[PMID 19458352
] Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants
| GWAS snp | |
|---|---|
| PMID | [PMID 20639880]
|
| Trait | Primary biliary cirrhosis |
| Title | Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis |
| Risk Allele | A |
| P-val | 8E-12 |
| Odds Ratio | 1.48 [NR] |
[PMID 21285166] Role of rs1343151 IL23R and rs3790567 IL12RB2 Polymorphisms in Biopsy-proven Giant Cell Arteritis
[PMID 18598732] Vaccine immunogenetics: bedside to bench to population.
[PMID 21506939] Replicated association of 17q12-21 with susceptibility of primary biliary cirrhosis in a Japanese cohort.
[PMID 22076442] A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.
Primary Biliary Cirrhosis: Preliminary Research
[PMID 23009887] Impact of cytokine and cytokine receptor gene polymorphisms on cellular immunity after smallpox vaccination.
[PMID 24997981] Association study between interleukin-12 receptor β1/β2 genes and allergic rhinitis in the Chinese Han population
[PMID 25720506] Autoimmune risk loci of IL12RB2, IKZF1, XKR6, TMEM39A and CSK in Chinese patients with systemic lupus erythematosus
[PMID 28299343] Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study.
