rs6441286
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 2.5 | 3.08x chance of developing primary biliary cirrhosis |
| (G;T) | 2 | 1.54x chance of developing primary biliary cirrhosis. |
| (T;T) | 1 | Normal chances of developing primary biliary cirrhosis |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 160011091 |
| Gene | IL12A-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6441286 |
| dbSNP (classic) | rs6441286 |
| ClinGen | rs6441286 |
| ebi | rs6441286 |
| HLI | rs6441286 |
| Exac | rs6441286 |
| Gnomad | rs6441286 |
| Varsome | rs6441286 |
| LitVar | rs6441286 |
| Map | rs6441286 |
| PheGenI | rs6441286 |
| Biobank | rs6441286 |
| 1000 genomes | rs6441286 |
| hgdp | rs6441286 |
| ensembl | rs6441286 |
| geneview | rs6441286 |
| scholar | rs6441286 |
| rs6441286 | |
| pharmgkb | rs6441286 |
| gwascentral | rs6441286 |
| openSNP | rs6441286 |
| 23andMe | rs6441286 |
| SNPshot | rs6441286 |
| SNPdbe | rs6441286 |
| MSV3d | rs6441286 |
| GWAS Ctlg | rs6441286 |
| GMAF | 0.3806 |
| Max Magnitude | 2.5 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
- Each G at rs2856683 increased the odds of primary biliary cirrhosis by 1.75x.
- Each G at rs6441286 increased the odds of primary biliary cirrhosis by 1.54x.
- Each A at rs3790567 increased the odds of primary biliary cirrhosis by 1.51x.
[PMID 19458352
] Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants
| GWAS snp | |
|---|---|
| PMID | [PMID 20639880]
|
| Trait | Primary biliary cirrhosis |
| Title | Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis |
| Risk Allele | G |
| P-val | 8E-12 |
| Odds Ratio | 1.44 [NR] |
[PMID 29059373] Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.
