rs3792267

Orientation

plus

Stabilized

plus

Make rs3792267(A;A)

Make rs3792267(A;G)

Make rs3792267(G;G)

Reference

GRCh38 38.1/141

Chromosome

2

Position

240591757

Gene

CAPN10

is a	snp
is	mentioned by
dbSNP	rs3792267
dbSNP (classic)	rs3792267
ClinGen	rs3792267
ebi	rs3792267
HLI	rs3792267
Exac	rs3792267
Gnomad	rs3792267
Varsome	rs3792267
LitVar	rs3792267
Map	rs3792267
PheGenI	rs3792267
Biobank	rs3792267
1000 genomes	rs3792267
hgdp	rs3792267
ensembl	rs3792267
geneview	rs3792267
scholar	rs3792267
google	rs3792267
pharmgkb	rs3792267
gwascentral	rs3792267
openSNP	rs3792267
23andMe	rs3792267
SNPshot	rs3792267
SNPdbe	rs3792267
MSV3d	rs3792267
GWAS Ctlg	rs3792267

GMAF

0.1993

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

[PMID 16857402] summary, indicating a small effect of this SNP, seen only in meta-analyses

rs3792267 associated with noninsulin-dependent diabetes mellitus, polycystic ovary syndrome, type 2 diabetes, gestational diabetes and obesity

OMIM	605286
Desc	CALPAIN 10; CAPN10
Variant
Related	also

[PMID 19752882] Association of calpain-10 gene polymorphism and posttransplant diabetes mellitus in kidney transplant patients medicated with tacrolimus

[PMID 20178008] Association of Diabetes Susceptibility Gene Calpain-10 with Pancreatic Cancer Among Smokers

[PMID 20470430] Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study

OMIM	605286
Desc
Variant	0001
Related	also

[PMID 14730479] Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies.

[PMID 15371359] Testing for Hardy-Weinberg equilibrium in samples with related individuals.

[PMID 17570749] Genetic prediction of future type 2 diabetes.

[PMID 17825092] Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography.

[PMID 18599530] Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

[PMID 18603647] Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.

[PMID 18936436] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.

[PMID 19193380] Replication of calpain-10 genetic association with carotid intima-media thickness.

[PMID 19387820] Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome.

[PMID 19643578] Genetic risk factors for type 2 diabetes with pharmacologic intervention in African-American patients with schizophrenia or schizoaffective disorder.

[PMID 20075150] Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.

[PMID 20119856] Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample.

[PMID 20142250] Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.

[PMID 20667559] Association of calpain 10 gene polymorphisms with type 2 diabetes mellitus in Southern Indians.

[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.

[PMID 21834909] A replication study of the IRS1, CAPN10, TCF7L2, and PPARG gene polymorphisms associated with type 2 diabetes in two different populations of Mexico.

[PMID 22391941] Meta-analysis of association studies between five candidate genes and type 2 diabetes in Chinese Han population.

[PMID 24612564] Association of IRS-1, CAPN10 and PPARG gene polymorphisms with T2DM in the high risk population of Hyderabad, India

ClinVar
Risk	rs3792267(A;A)
Alt	rs3792267(A;A)
Reference	rs3792267(G;G)
Significance	Other
Disease	Diabetes mellitus type 2
Variation	info
Gene	CAPN10
CLNDBN	Diabetes mellitus type 2
Reversed	0
HGVS	NC_000002.11:g.241531174G>A
CLNSRC	OMIM Allelic Variant
CLNACC	RCV000005398.2,

[PMID 31292430] The Association Between the rs2975760 and rs3792267 Single Nucleotide Polymorphisms of Calpain 10 (CAPN10) and Gestational Diabetes Mellitus.