rs3834458
| Orientation | plus |
| Stabilized | plus |
| Make rs3834458(-;-) |
| Make rs3834458(-;T) |
| Make rs3834458(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 61827449 |
| Gene | FADS2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3834458 |
| dbSNP (classic) | rs3834458 |
| ClinGen | rs3834458 |
| ebi | rs3834458 |
| HLI | rs3834458 |
| Exac | rs3834458 |
| Gnomad | rs3834458 |
| Varsome | rs3834458 |
| LitVar | rs3834458 |
| Map | rs3834458 |
| PheGenI | rs3834458 |
| Biobank | rs3834458 |
| 1000 genomes | rs3834458 |
| hgdp | rs3834458 |
| ensembl | rs3834458 |
| geneview | rs3834458 |
| scholar | rs3834458 |
| rs3834458 | |
| pharmgkb | rs3834458 |
| gwascentral | rs3834458 |
| openSNP | rs3834458 |
| 23andMe | rs3834458 |
| SNPshot | rs3834458 |
| SNPdbe | rs3834458 |
| MSV3d | rs3834458 |
| GWAS Ctlg | rs3834458 |
| GMAF | 0.331 |
| Max Magnitude | 0 |
[PMID 19546342
] A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1
[PMID 20335541] FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk
[PMID 21629299] Fatty acid desaturase 2 promoter mutation is not responsible for ?6-desaturase deficiency
The previous supersedes
[PMID 12951357] A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency
[PMID 20565855] Genetic variation in lipid desaturases and its impact on the development of human disease.
[PMID 21793953] FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children.
[PMID 23285256] Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism
[PMID 23160180] Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.
[PMID 23636240] FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants.
