rs41295061
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| Make rs41295061(A;A) |
| Make rs41295061(A;C) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 6072697 |
| Gene | RPL32P23 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs41295061 |
| dbSNP (classic) | rs41295061 |
| ClinGen | rs41295061 |
| ebi | rs41295061 |
| HLI | rs41295061 |
| Exac | rs41295061 |
| Gnomad | rs41295061 |
| Varsome | rs41295061 |
| LitVar | rs41295061 |
| Map | rs41295061 |
| PheGenI | rs41295061 |
| Biobank | rs41295061 |
| 1000 genomes | rs41295061 |
| hgdp | rs41295061 |
| ensembl | rs41295061 |
| geneview | rs41295061 |
| scholar | rs41295061 |
| rs41295061 | |
| pharmgkb | rs41295061 |
| gwascentral | rs41295061 |
| openSNP | rs41295061 |
| 23andMe | rs41295061 |
| SNPshot | rs41295061 |
| SNPdbe | rs41295061 |
| MSV3d | rs41295061 |
| GWAS Ctlg | rs41295061 |
| GMAF | 0.03306 |
| Max Magnitude | 0 |
rs41295061 increases susceptibility to Type I Diabetes 1.67 times for heterozygotes (AC) and 2.27 times for homozygotes (CC) [PMID 17676041]
[PMID 19265545
] Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.
[PMID 19794070] A cis-Acting Regulatory Variant in the IL2RA Locus
[PMID 20033399] Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects
[PMID 18556337] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).
[PMID 18776148] Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms.
[PMID 19106270] Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.
[PMID 19116909] Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
[PMID 19119414] IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.
[PMID 19125193] IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).
[PMID 19956099] The type I diabetes association of the IL2RA locus.
[PMID 19956106] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
[PMID 20179739] Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.
[PMID 20236493] The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis.
[PMID 20849903] Association of IL-2RA/CD25 with type 1 diabetes in the Belgian population.
[PMID 21815908] A variant of the Il2ra / Cd25 gene predisposing to graves' disease is associated with increased levels of soluble interleukin-2 receptor.
[PMID 21875375] Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients.
| ClinVar | |
|---|---|
| Risk | rs41295061(A;A) |
| Alt | rs41295061(A;A) |
| Reference | Rs41295061(C;C) |
| Significance | Other |
| Disease | Diabetes mellitus |
| Variation | info |
| Gene | |
| CLNDBN | Diabetes mellitus, insulin-dependent, 10 |
| Reversed | 0 |
| HGVS | NC_000010.10:g.6114660C>A |
| CLNSRC | OMIM Allelic Variant |
| CLNACC | RCV000015781.21, |
