rs4151620
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;G) |
| Make rs4151620(C;C) |
| Make rs4151620(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 13 |
| Position | 48474923 |
| Gene | RB1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4151620 |
| dbSNP (classic) | rs4151620 |
| ClinGen | rs4151620 |
| ebi | rs4151620 |
| HLI | rs4151620 |
| Exac | rs4151620 |
| Gnomad | rs4151620 |
| Varsome | rs4151620 |
| LitVar | rs4151620 |
| Map | rs4151620 |
| PheGenI | rs4151620 |
| Biobank | rs4151620 |
| 1000 genomes | rs4151620 |
| hgdp | rs4151620 |
| ensembl | rs4151620 |
| geneview | rs4151620 |
| scholar | rs4151620 |
| rs4151620 | |
| pharmgkb | rs4151620 |
| gwascentral | rs4151620 |
| openSNP | rs4151620 |
| 23andMe | rs4151620 |
| SNPshot | rs4151620 |
| SNPdbe | rs4151620 |
| MSV3d | rs4151620 |
| GWAS Ctlg | rs4151620 |
| GMAF | 0.1001 |
| Max Magnitude | 0 |
rs4151620(C;G) and rs4151620(G;G) are associated with a reduced risk of ovarian cancer compared with rs4151620(G;G) individuals.
This snp has been linked to ovarian cancer [PMID 17047088]
Intron 17 of RB1 contains the open reading frame for the P2RY5 gene, and rs4151620 is perfectly correlated with rs2227311, which is located in the 5'-untranslated region of P2RY5 and is predicted to affect P2RY5 transcription. rs2854344 has been reported previously to be associated with breast cancer risk [PMID 16685266
]
[PMID 18281541] Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.
[PMID 19258477] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
