rs4251961
| Orientation | plus |
| Stabilized | plus |
| Make rs4251961(C;C) |
| Make rs4251961(C;T) |
| Make rs4251961(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 113116890 |
| Gene | IL1RN |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4251961 |
| dbSNP (classic) | rs4251961 |
| ClinGen | rs4251961 |
| ebi | rs4251961 |
| HLI | rs4251961 |
| Exac | rs4251961 |
| Gnomad | rs4251961 |
| Varsome | rs4251961 |
| LitVar | rs4251961 |
| Map | rs4251961 |
| PheGenI | rs4251961 |
| Biobank | rs4251961 |
| 1000 genomes | rs4251961 |
| hgdp | rs4251961 |
| ensembl | rs4251961 |
| geneview | rs4251961 |
| scholar | rs4251961 |
| rs4251961 | |
| pharmgkb | rs4251961 |
| gwascentral | rs4251961 |
| openSNP | rs4251961 |
| 23andMe | rs4251961 |
| SNPshot | rs4251961 |
| SNPdbe | rs4251961 |
| MSV3d | rs4251961 |
| GWAS Ctlg | rs4251961 |
| GMAF | 0.23 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 21248262] The IL1RN Promoter rs4251961 Correlates with IL-1 Receptor Antagonist Concentrations in Human Infection and Is Differentially Regulated by GATA-1
[PMID 21968104
] The association of genetic variants in interleukin-1 genes with cognition: findings from the cardiovascular health study
[PMID 17443229] Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels.
[PMID 18451331] Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation.
[PMID 18635889] Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
[PMID 18853133] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
[PMID 19104506] Variations in the interleukin-1 receptor antagonist gene impact on survival of patients with advanced colorectal cancer.
[PMID 19347053] Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion.
[PMID 19729864] Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.
[PMID 19934104] Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.
[PMID 20031576] Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.
[PMID 20031590] The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations.
[PMID 22205395] Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans.
[PMID 24233813] Stroke, IL-1ra, IL1RN, Infection and Outcome
[PMID 23602982] IL-1 receptor antagonist gene as a predictive biomarker of progression of knee osteoarthritis in a population cohort
[PMID 24776844] Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease
[PMID 25542762] Poststroke fatigue: hints to a biological mechanism.
[PMID 27775822] Polymorphisms in the interleukin (IL)-1 gene cluster influence systemic inflammation in patients at risk for acute-on-chronic liver failure.
[PMID 28060727] Associations between genetic variants in immunoregulatory genes and risk of non-Hodgkin lymphoma in a Chinese population.
[PMID 29117667] Association of a genetic polymorphism of IL1RN with risk of acute pancreatitis in a Korean ethnic group.
[PMID 32655394] Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding: A Case-Control Study.
