rs4362

plus

Geno	Mag	Summary
(T;T)	0	common in clinvar

Make rs4362(C;C)

Make rs4362(C;T)

Reference

GRCh38 38.1/141

Chromosome

17

Position

63496400

Gene

ACE

is a	snp
is	mentioned by
dbSNP	rs4362
dbSNP (classic)	rs4362
ClinGen	rs4362
ebi	rs4362
HLI	rs4362
Exac	rs4362
Gnomad	rs4362
Varsome	rs4362
LitVar	rs4362
Map	rs4362
PheGenI	rs4362
Biobank	rs4362
1000 genomes	rs4362
hgdp	rs4362
ensembl	rs4362
geneview	rs4362
scholar	rs4362
google	rs4362
pharmgkb	rs4362
gwascentral	rs4362
openSNP	rs4362
23andMe	rs4362
SNPshot	rs4362
SNPdbe	rs4362
MSV3d	rs4362
GWAS Ctlg	rs4362

GMAF

0.4408

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 24622918] Renin-Angiotensin System Genetic Polymorphisms and Brain White Matter Lesions in Older Australians [PMID 18057531 ] Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS).

[PMID 18076107 ] Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis.

[PMID 19105203 ] An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.

[PMID 19132786] Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians.

[PMID 20416077 ] Identification of type 2 diabetes-associated combination of SNPs using support vector machine.

GWAS snp
PMID	[PMID 24816252 ]
Trait	Blood metabolite levels
Title	An atlas of genetic influences on human blood metabolites.
Risk Allele	T
P-val	1E-21
Odds Ratio	.06 [0.049-0.073] unit increase

ClinVar
Risk	rs4362(C;C)
Alt	rs4362(C;C)
Reference	Rs4362(T;T)
Significance	Non-pathogenic
Disease	not specified Renal dysplasia
Variation	info
Gene	ACE
CLNDBN	not specified Renal dysplasia
Reversed	0
HGVS	NC_000017.10:g.61573761T>C
CLNSRC
CLNACC	RCV000243922.1, RCV000342807.1,