rs4415084
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 |
| Make rs4415084(C;T) |
| Make rs4415084(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 44662413 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4415084 |
| dbSNP (classic) | rs4415084 |
| ClinGen | rs4415084 |
| ebi | rs4415084 |
| HLI | rs4415084 |
| Exac | rs4415084 |
| Gnomad | rs4415084 |
| Varsome | rs4415084 |
| LitVar | rs4415084 |
| Map | rs4415084 |
| PheGenI | rs4415084 |
| Biobank | rs4415084 |
| 1000 genomes | rs4415084 |
| hgdp | rs4415084 |
| ensembl | rs4415084 |
| geneview | rs4415084 |
| scholar | rs4415084 |
| rs4415084 | |
| pharmgkb | rs4415084 |
| gwascentral | rs4415084 |
| openSNP | rs4415084 |
| 23andMe | rs4415084 |
| SNPshot | rs4415084 |
| SNPdbe | rs4415084 |
| MSV3d | rs4415084 |
| GWAS Ctlg | rs4415084 |
| GMAF | 0.4871 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs4415084 and rs10941679 confer risk for estrogen receptor breast cancer (ER)-positive tumors (OR = 1.27, P = 2.5E-12 for rs10941679) based on a study of 6,145 cases. [PMID 18438407] From a DeCode user report, the risk allele appears to be T; this T;T individual reportedly has a 1.19x increased risk of breast cancer.
[PMID 20095854
] Novel Breast Cancer Risk Alleles and Interaction with Ionizing Radiation among U.S. Radiologic Technologists
[PMID 20140701] Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women's Health Study
| GWAS snp | |
|---|---|
| PMID | [PMID 21263130] |
| Trait | |
| Title | Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study |
| Risk Allele | T |
| P-val | 8E-11 |
| Odds Ratio | 1.1700 [1.11-1.22] |
[PMID 21791674] Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium
[PMID 22832384] Genetic variants at 5p12 and risk of breast cancer in Han Chinese
the two risk SNPs reported in the European population were neither associated with breast cancer risk in our Chinese population
[PMID 19330030] A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).
[PMID 20085711] Leveraging genetic variability across populations for the identification of causal variants.
[PMID 22965832] Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.
[PMID 25002657] Breast cancer susceptibility variants and mammographic density phenotypes in Norwegian postmenopausal women
[PMID 29351903] Integrative genomic analysis predicts causative cis-regulatory mechanisms of the breast cancer-associated genetic variant rs4415084.
[PMID 29372690] Association of single nucleotide polymorphisms in FGF-RAS/MAP signalling cascade with breast cancer susceptibility.
