rs4487645
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs4487645(A;A) |
| Make rs4487645(A;C) |
| Make rs4487645(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 21898622 |
| Gene | DNAH11 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4487645 |
| dbSNP (classic) | rs4487645 |
| ClinGen | rs4487645 |
| ebi | rs4487645 |
| HLI | rs4487645 |
| Exac | rs4487645 |
| Gnomad | rs4487645 |
| Varsome | rs4487645 |
| LitVar | rs4487645 |
| Map | rs4487645 |
| PheGenI | rs4487645 |
| Biobank | rs4487645 |
| 1000 genomes | rs4487645 |
| hgdp | rs4487645 |
| ensembl | rs4487645 |
| geneview | rs4487645 |
| scholar | rs4487645 |
| rs4487645 | |
| pharmgkb | rs4487645 |
| gwascentral | rs4487645 |
| openSNP | rs4487645 |
| 23andMe | rs4487645 |
| SNPshot | rs4487645 |
| SNPdbe | rs4487645 |
| MSV3d | rs4487645 |
| GWAS Ctlg | rs4487645 |
| GMAF | 0.2268 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 22120009 ]
|
| Trait | |
| Title | Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk. |
| Risk Allele | C |
| P-val | 3E-14 |
| Odds Ratio | 1.3800 None |
| GWAS snp | |
|---|---|
| PMID | [PMID 23502783]
|
| Trait | Multiple myeloma (hyperdiploidy) |
| Title | The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. |
| Risk Allele | C |
| P-val | 1E-9 |
| Odds Ratio | 1.43 [1.27-1.60] |
[PMID 24449210] Inherited genetic susceptibility to monoclonal gammopathy of unknown significance
[PMID 25480495] The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells
