rs4489954
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 1 | Normal risk of developing restless legs syndrome |
| (G;T) | 1.5 | 0.69x risk risk of developing restless legs syndrome |
| (T;T) | 1.8 | >0.69x risk of developing restless legs syndrome |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 67779737 |
| Gene | MAP2K5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4489954 |
| dbSNP (classic) | rs4489954 |
| ClinGen | rs4489954 |
| ebi | rs4489954 |
| HLI | rs4489954 |
| Exac | rs4489954 |
| Gnomad | rs4489954 |
| Varsome | rs4489954 |
| LitVar | rs4489954 |
| Map | rs4489954 |
| PheGenI | rs4489954 |
| Biobank | rs4489954 |
| 1000 genomes | rs4489954 |
| hgdp | rs4489954 |
| ensembl | rs4489954 |
| geneview | rs4489954 |
| scholar | rs4489954 |
| rs4489954 | |
| pharmgkb | rs4489954 |
| gwascentral | rs4489954 |
| openSNP | rs4489954 |
| 23andMe | rs4489954 |
| SNPshot | rs4489954 |
| SNPdbe | rs4489954 |
| MSV3d | rs4489954 |
| GWAS Ctlg | rs4489954 |
| GMAF | 0.4637 |
| Max Magnitude | 1.8 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs4489954, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.69 (CI: 0.69-0.82) for the (T) minor allele. [PMID 17637780]
[PMID 19223043] Exploring the genetic link between RLS and ADHD
