rs4624820

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)		increased testicular cancer risk for men
(A;G)		1.37x increased testicular cancer risk for men

Make rs4624820(G;G)

Reference

GRCh38 38.1/141

Chromosome

5

Position

142302223

is a	snp
is	mentioned by
dbSNP	rs4624820
dbSNP (classic)	rs4624820
ClinGen	rs4624820
ebi	rs4624820
HLI	rs4624820
Exac	rs4624820
Gnomad	rs4624820
Varsome	rs4624820
LitVar	rs4624820
Map	rs4624820
PheGenI	rs4624820
Biobank	rs4624820
1000 genomes	rs4624820
hgdp	rs4624820
ensembl	rs4624820
geneview	rs4624820
scholar	rs4624820
google	rs4624820
pharmgkb	rs4624820
gwascentral	rs4624820
openSNP	rs4624820
23andMe	rs4624820
SNPshot	rs4624820
SNPdbe	rs4624820
MSV3d	rs4624820
GWAS Ctlg	rs4624820

GMAF

0.4844

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

23andMe blog each rs4624820(A) increases the odds of testicular cancer by 1.37x

GWAS snp
PMID	[PMID 19483681]
Trait	Testicular germ cell tumor
Title	A genome-wide association study of testicular germ cell tumor
Risk Allele	A
P-val	3E-13
Odds Ratio	1.37 [1.19-1.58]

GWAS snp
PMID	[PMID 20543847]
Trait	Testicular germ cell cancer
Title	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer
Risk Allele
P-val	1E-14
Odds Ratio	1.47 [1.33-1.64]

OMIM	273300
Desc
Variant
Related	also

GWAS snp
PMID	[PMID 23666239]
Trait	Testicular germ cell tumor
Title	Meta-analysis identifies four new loci associated with testicular germ cell tumor.
Risk Allele	G
P-val	8E-10
Odds Ratio	1.64 [1.39-1.89]

GWAS snp
PMID	[PMID 23666240]
Trait	Testicular germ cell tumor
Title	Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.
Risk Allele	A
P-val	3E-31
Odds Ratio	1.52 [1.38-1.67]

[PMID 28295819] Variants in BAK1, SPRY4, and GAB2 are Associated with Pediatric Germ Cell Tumors: A Report from the Children's Oncology Group.