rs4646421
| Orientation | minus |
| Stabilized | minus |
| Make rs4646421(C;C) |
| Make rs4646421(C;T) |
| Make rs4646421(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 74723851 |
| Gene | CYP1A1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4646421 |
| dbSNP (classic) | rs4646421 |
| ClinGen | rs4646421 |
| ebi | rs4646421 |
| HLI | rs4646421 |
| Exac | rs4646421 |
| Gnomad | rs4646421 |
| Varsome | rs4646421 |
| LitVar | rs4646421 |
| Map | rs4646421 |
| PheGenI | rs4646421 |
| Biobank | rs4646421 |
| 1000 genomes | rs4646421 |
| hgdp | rs4646421 |
| ensembl | rs4646421 |
| geneview | rs4646421 |
| scholar | rs4646421 |
| rs4646421 | |
| pharmgkb | rs4646421 |
| gwascentral | rs4646421 |
| openSNP | rs4646421 |
| 23andMe | rs4646421 |
| SNPshot | rs4646421 |
| SNPdbe | rs4646421 |
| MSV3d | rs4646421 |
| GWAS Ctlg | rs4646421 |
| GMAF | 0.2736 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19110417] hepatocellular carcinoma in Chinese populations
- increased risk rs4646421 (OR 1.30, 95% CI 1.05-1.61)
- increased risk rs2198843 (OR 1.33, 95% CI 1.05-1.69)
- reduced risk rs4886605 (OR 0.70. 95% CI 0.52-0.94)
[PMID 17160896
] Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants.
[PMID 18268125] Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.
[PMID 18632753] Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
[PMID 18691756] Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk.
[PMID 18778477] Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.
[PMID 18798002] Coffee consumption, genetic susceptibility and bladder cancer risk.
[PMID 19330903] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
[PMID 19567509] Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.
[PMID 24320736] Role of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in Han Chinese: A case-control study
[PMID 23816456] CYP1A1 genetic polymorphism and polycyclic aromatic hydrocarbons on pulmonary function in the elderly: haplotype-based approach for gene-environment interaction
[PMID 22521834] Genetic variations of CYP2B6 gene were associated with plasma BPDE-Alb adducts and DNA damage levels in coke oven workers.
[PMID 29581776] Association of Smoking and XPG, CYP1A1, OGG1, ERCC5, ERCC1, MMP2, and MMP9 Gene Polymorphisms with the early detection and occurrence of Laryngeal Squamous Carcinoma.
