rs4684677
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common on affy axiom data |
| Make rs4684677(A;A) |
| Make rs4684677(A;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 10286769 |
| Gene | GHRL, GHRLOS |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4684677 |
| dbSNP (classic) | rs4684677 |
| ClinGen | rs4684677 |
| ebi | rs4684677 |
| HLI | rs4684677 |
| Exac | rs4684677 |
| Gnomad | rs4684677 |
| Varsome | rs4684677 |
| LitVar | rs4684677 |
| Map | rs4684677 |
| PheGenI | rs4684677 |
| Biobank | rs4684677 |
| 1000 genomes | rs4684677 |
| hgdp | rs4684677 |
| ensembl | rs4684677 |
| geneview | rs4684677 |
| scholar | rs4684677 |
| rs4684677 | |
| pharmgkb | rs4684677 |
| gwascentral | rs4684677 |
| openSNP | rs4684677 |
| 23andMe | rs4684677 |
| SNPshot | rs4684677 |
| SNPdbe | rs4684677 |
| MSV3d | rs4684677 |
| GWAS Ctlg | rs4684677 |
| Merged from | Rs17847133 |
| GMAF | 0.0652 |
| Max Magnitude | 0 |
| ? | (A;A) (A;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 20010782] Influence of ghrelin gene polymorphisms on hypertension and atherosclerotic disease
[PMID 22005651] Genetic association between ghrelin polymorphisms and Alzheimer's disease in a Japanese population
| ClinVar | |
|---|---|
| Risk | rs4684677(A;A) |
| Alt | rs4684677(A;A) |
| Reference | Rs4684677(T;T) |
| Significance | Other |
| Disease | Obesity |
| Variation | info |
| Gene | GHRLOS GHRL |
| CLNDBN | Obesity |
| Reversed | 0 |
| HGVS | NC_000003.11:g.10328453T>A |
| CLNSRC | OMIM Allelic Variant |
| CLNACC | RCV000023422.2, |
[PMID 16204371] Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish.
[PMID 17389697] Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes.
[PMID 18239581] Lack of association of ghrelin precursor gene variants and percentage body fat or serum lipid profiles.
[PMID 19041386
] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19165163] Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.
[PMID 19593725] Association of maternally inherited GNAS alleles with African-American male birth weight.
[PMID 20586762] Genetic variation of the ghrelin signaling system in females with severe alcohol dependence.
[PMID 21448464] The ghrelin signalling system is involved in the consumption of sweets.
[PMID 23251435] A Natural Variant of Obestatin, Q90L, Inhibits Ghrelin's Action on Food Intake and GH Secretion and Targets NPY and GHRH Neurons in Mice
[PMID 23084284] A possible association between panic disorder and a polymorphism in the preproghrelingene.
[PMID 25868387] The association between rs4684677 T/A polymorphism in preproghrelin gene and predisposition to autoimmune thyroid diseases in children
[PMID 26059200] Genetic variation of the growth hormone secretagogue receptor gene is associated with alcohol use disorders identification test scores and smoking
