rs4788102
| Orientation | plus |
| Stabilized | plus |
| Make rs4788102(A;A) |
| Make rs4788102(A;G) |
| Make rs4788102(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 28862077 |
| Gene | SH2B1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4788102 |
| dbSNP (classic) | rs4788102 |
| ClinGen | rs4788102 |
| ebi | rs4788102 |
| HLI | rs4788102 |
| Exac | rs4788102 |
| Gnomad | rs4788102 |
| Varsome | rs4788102 |
| LitVar | rs4788102 |
| Map | rs4788102 |
| PheGenI | rs4788102 |
| Biobank | rs4788102 |
| 1000 genomes | rs4788102 |
| hgdp | rs4788102 |
| ensembl | rs4788102 |
| geneview | rs4788102 |
| scholar | rs4788102 |
| rs4788102 | |
| pharmgkb | rs4788102 |
| gwascentral | rs4788102 |
| openSNP | rs4788102 |
| 23andMe | rs4788102 |
| SNPshot | rs4788102 |
| SNPdbe | rs4788102 |
| MSV3d | rs4788102 |
| GWAS Ctlg | rs4788102 |
| GMAF | 0.2649 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
association with obesity [PMID 19079260]
[PMID 21907990
] The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells
[PMID 17228025] The SH2B gene is associated with serum leptin and body fat in normal female twins.
[PMID 19478790] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
[PMID 23054017] The joint effect of cigarette smoking and polymorphisms on LRP5, LEPR, near MC4R and SH2B1 genes on metabolic syndrome susceptibility in Taiwan
[PMID 23424664] Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children
[PMID 24103803] The SH2B1 obesity locus and abnormal glucose homeostasis: Lack of evidence for association from a meta-analysis in individuals of European ancestry
[PMID 24269186] An obesity genetic risk score is associated with metabolic syndrome in Chinese children
[PMID 23121087] Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.
[PMID 25492288] [Impact of obesity-related gene polymorphism on risk of obesity and metabolic disorder in childhood]
