rs4833095
| Orientation | plus |
| Stabilized | plus |
| Make rs4833095(C;C) |
| Make rs4833095(C;T) |
| Make rs4833095(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 38798089 |
| Gene | TLR1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4833095 |
| dbSNP (classic) | rs4833095 |
| ClinGen | rs4833095 |
| ebi | rs4833095 |
| HLI | rs4833095 |
| Exac | rs4833095 |
| Gnomad | rs4833095 |
| Varsome | rs4833095 |
| LitVar | rs4833095 |
| Map | rs4833095 |
| PheGenI | rs4833095 |
| Biobank | rs4833095 |
| 1000 genomes | rs4833095 |
| hgdp | rs4833095 |
| ensembl | rs4833095 |
| geneview | rs4833095 |
| scholar | rs4833095 |
| rs4833095 | |
| pharmgkb | rs4833095 |
| gwascentral | rs4833095 |
| openSNP | rs4833095 |
| 23andMe | rs4833095 |
| SNPshot | rs4833095 |
| SNPdbe | rs4833095 |
| MSV3d | rs4833095 |
| GWAS Ctlg | rs4833095 |
| GMAF | 0.4711 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 21371045] TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy
[PMID 17554260
] Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
[PMID 18396467] Genetic variation and haplotype structures of innate immunity genes in eastern India.
[PMID 18635889] Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
[PMID 18752252] Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.
[PMID 19134200] No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.
[PMID 19503599] The impact of divergence time on the nature of population structure: an example from Iceland.
[PMID 19543401] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.
[PMID 19567509] Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.
[PMID 20200442] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.
[PMID 20459687] Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.
[PMID 20478407] The toll-like receptor 1 variant S248N influences placental malaria.
[PMID 20617178] Leprosy and the adaptation of human toll-like receptor 1.
[PMID 21108742] Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: a case-control study in the Korean population.
[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
[PMID 23478521] Toll-Like Receptor 1 Polymorphisms and Associated Outcomes in Sepsis After Traumatic Injury: A Candidate Gene Association Study
| ClinVar | |
|---|---|
| Risk | rs4833095(C;C) |
| Alt | rs4833095(C;C) |
| Reference | rs4833095(T;T) |
| Significance | Other |
| Disease | Leprosy 5 |
| Variation | info |
| Gene | TLR1 |
| CLNDBN | Leprosy 5 |
| Reversed | 0 |
| HGVS | NC_000004.11:g.38799710T>C |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000008866.2, |
[PMID 23255565] Racial variation in toll-like receptor variants among women with pelvic inflammatory disease.
[PMID 25028161] Polymorphisms in TLR1, TLR6 and TLR10 genes and the risk of Graves' disease
| GWAS snp | |
|---|---|
| PMID | [PMID 24388013]
|
| Trait | Asthma and hay fever |
| Title | Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. |
| Risk Allele | T |
| P-val | 5E-12 |
| Odds Ratio | 1.20 [1.14-1.26] |
[PMID 25687912] Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population
[PMID 24780078] Association between TLR1 polymorphisms and alopecia areata
[PMID 30208882] Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis.
[PMID 30289892] The TLR1 gene is associated with higher protection from leprosy in women.
[PMID 30574617] TLR1 and PRKAA1 Gene Polymorphisms in the Development of Atrophic Gastritis and Gastric Cancer.
