rs4864548
From SNPedia
| discrepancy in risk assignment |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal | |
| (A;G) | 1.8x higher risk for obesity if in haplotype | |
| (G;G) | 0 | 1.8x higher risk for obesity if in haplotype |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 55547636 |
| Gene | CLOCK |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4864548 |
| dbSNP (classic) | rs4864548 |
| ClinGen | rs4864548 |
| ebi | rs4864548 |
| HLI | rs4864548 |
| Exac | rs4864548 |
| Gnomad | rs4864548 |
| Varsome | rs4864548 |
| LitVar | rs4864548 |
| Map | rs4864548 |
| PheGenI | rs4864548 |
| Biobank | rs4864548 |
| 1000 genomes | rs4864548 |
| hgdp | rs4864548 |
| ensembl | rs4864548 |
| geneview | rs4864548 |
| scholar | rs4864548 |
| rs4864548 | |
| pharmgkb | rs4864548 |
| gwascentral | rs4864548 |
| openSNP | rs4864548 |
| 23andMe | rs4864548 |
| SNPshot | rs4864548 |
| SNPdbe | rs4864548 |
| MSV3d | rs4864548 |
| GWAS Ctlg | rs4864548 |
| GMAF | 0.3861 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
A study of 391 overweight patients concluded that the haplotype of rs1554483(G) and rs4864548(A) was associated with a 1.8-fold higher risk (CI: 1.31-2.54, p < 0.001) of obesity.[PMID 18541547]
[PMID 17696255
] Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease.
[PMID 18071340] Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.
