rs4917639
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs4917639(A;C) |
| Make rs4917639(C;C) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 94965778 |
| Gene | CYP2C9 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4917639 |
| dbSNP (classic) | rs4917639 |
| ClinGen | rs4917639 |
| ebi | rs4917639 |
| HLI | rs4917639 |
| Exac | rs4917639 |
| Gnomad | rs4917639 |
| Varsome | rs4917639 |
| LitVar | rs4917639 |
| Map | rs4917639 |
| PheGenI | rs4917639 |
| Biobank | rs4917639 |
| 1000 genomes | rs4917639 |
| hgdp | rs4917639 |
| ensembl | rs4917639 |
| geneview | rs4917639 |
| scholar | rs4917639 |
| rs4917639 | |
| pharmgkb | rs4917639 |
| gwascentral | rs4917639 |
| openSNP | rs4917639 |
| 23andMe | rs4917639 |
| SNPshot | rs4917639 |
| SNPdbe | rs4917639 |
| MSV3d | rs4917639 |
| GWAS Ctlg | rs4917639 |
| GMAF | 0.1694 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 22321278] [Impact of CYP2C9 and VKORC1 polymorphism on warfarin response during initiation of therapy]
[PMID 17048007
] Association of warfarin dose with genes involved in its action and metabolism.
[PMID 18574025] The largest prospective warfarin-treated cohort supports genetic forecasting.
[PMID 19300499] A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
[PMID 22178823] [Distribution of variant alleles association with warfarin pharmacokinetics and pharmacodynamics in the Han population in China].
| ClinVar | |
|---|---|
| Risk | rs4917639(C;C) |
| Alt | rs4917639(C;C) |
| Reference | Rs4917639(A;A) |
| Significance | Drug-response |
| Disease | warfarin response - Dosage |
| Variation | info |
| Gene | CYP2C9 |
| CLNDBN | warfarin response - Dosage |
| Reversed | 0 |
| HGVS | NC_000010.10:g.96725535A>C |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211417.1, |
