rs4959039

plus

Geno	Mag	Summary
(A;A)	0	normal
(A;G)	1.4	1.4x higher risk for multiple sclerosis
(G;G)	1.6	1.6x higher risk for multiple sclerosis

Reference

GRCh38 38.1/141

Chromosome

6

Position

29989292

is a	snp
is	mentioned by
dbSNP	rs4959039
dbSNP (classic)	rs4959039
ClinGen	rs4959039
ebi	rs4959039
HLI	rs4959039
Exac	rs4959039
Gnomad	rs4959039
Varsome	rs4959039
LitVar	rs4959039
Map	rs4959039
PheGenI	rs4959039
Biobank	rs4959039
1000 genomes	rs4959039
hgdp	rs4959039
ensembl	rs4959039
geneview	rs4959039
scholar	rs4959039
google	rs4959039
pharmgkb	rs4959039
gwascentral	rs4959039
openSNP	rs4959039
23andMe	rs4959039
SNPshot	rs4959039
SNPdbe	rs4959039
MSV3d	rs4959039
GWAS Ctlg	rs4959039

GMAF

0.2617

Max Magnitude

1.6

?

(A;A) (A;G) (G;G)

28

rs4959039 is a SNP located within the Class I HLA-G region of chromosome 6.

Independently of the influence of the (nearby) HLA-DRB1*1501 allele, the rs4959039(G) was shown to be associated with increased risk for multiple sclerosis in a study of ~2,300 patients.[PMID 20593013 ]