rs4973768

Orientation

plus

Stabilized

plus

Make rs4973768(C;C)

Make rs4973768(C;T)

Make rs4973768(T;T)

Reference

GRCh38 38.1/141

Chromosome

3

Position

27374522

Gene

SLC4A7

is a	snp
is	mentioned by
dbSNP	rs4973768
dbSNP (classic)	rs4973768
ClinGen	rs4973768
ebi	rs4973768
HLI	rs4973768
Exac	rs4973768
Gnomad	rs4973768
Varsome	rs4973768
LitVar	rs4973768
Map	rs4973768
PheGenI	rs4973768
Biobank	rs4973768
1000 genomes	rs4973768
hgdp	rs4973768
ensembl	rs4973768
geneview	rs4973768
scholar	rs4973768
google	rs4973768
pharmgkb	rs4973768
gwascentral	rs4973768
openSNP	rs4973768
23andMe	rs4973768
SNPshot	rs4973768
SNPdbe	rs4973768
MSV3d	rs4973768
GWAS Ctlg	rs4973768

GMAF

0.3669

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 20453838]
Trait	Breast cancer
Title	Genome-wide association study identifies five new breast cancer susceptibility loci
Risk Allele	T
P-val	6E-7
Odds Ratio	1.16 [1.10-1.24]

[PMID 20699374] Evaluation of Breast Cancer Susceptibility Loci in Chinese Women

[PMID 21118973] Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

OMIM	114480
Desc
Variant
Related	also

GWAS snp
PMID	[PMID 21263130]
Trait
Title	Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study
Risk Allele	C
P-val	2E-8
Odds Ratio	1.1400 [1.09-1.19]

[PMID 21415360] Common genetic variants associated with breast cancer in Korean women and differential susceptibility according to intrinsic subtype

[PMID 21445572] Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies

[PMID 21791674] Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium

[PMID 22287734] Evaluation of Breast Cancer Susceptibility Loci on 2q35, 3p24, 17q23 and FGFR2 Genes in Taiwanese Women with Breast Cancer

[PMID 19330027] Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.

[PMID 20146796] Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.

[PMID 21596841] Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

[PMID 22160591] A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population.

[PMID 22532573] The role of genetic breast cancer susceptibility variants as prognostic factors.

[PMID 23117855] The SLC4A7 variant rs4973768 is associated with breast cancer risk: evidence from a case-control study and a meta-analysis

GWAS snp
PMID	[PMID 23535729]
Trait	Breast cancer
Title	Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Risk Allele	T
P-val	2E-30
Odds Ratio	1.10 [1.08-1.12]

[PMID 25784121] Associations between breast density and a panel of single nucleotide polymorphisms linked to breast cancer risk: a cohort study with digital mammography

[PMID 25881232] Associations between breast density and a panel of single nucleotide polymorphisms linked to breast cancer risk: a cohort study with digital mammography

[PMID 24895409] Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women

[PMID 27609814] Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR dependent processes.

[PMID 27863437] Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population.

[PMID 28757652] Genetic Breast Cancer Susceptibility Variants and Prognosis in the Prospectively Randomized SUCCESS A Study.

[PMID 32366738] Low-penetrance susceptibility variants and postmenopausal oestrogen receptor positive breast cancer.