rs568408
| Orientation | plus |
| Stabilized | plus |
| Make rs568408(A;A) |
| Make rs568408(A;G) |
| Make rs568408(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 159995680 |
| Gene | IL12A, IL12A-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs568408 |
| dbSNP (classic) | rs568408 |
| ClinGen | rs568408 |
| ebi | rs568408 |
| HLI | rs568408 |
| Exac | rs568408 |
| Gnomad | rs568408 |
| Varsome | rs568408 |
| LitVar | rs568408 |
| Map | rs568408 |
| PheGenI | rs568408 |
| Biobank | rs568408 |
| 1000 genomes | rs568408 |
| hgdp | rs568408 |
| ensembl | rs568408 |
| geneview | rs568408 |
| scholar | rs568408 |
| rs568408 | |
| pharmgkb | rs568408 |
| gwascentral | rs568408 |
| openSNP | rs568408 |
| 23andMe | rs568408 |
| SNPshot | rs568408 |
| SNPdbe | rs568408 |
| MSV3d | rs568408 |
| GWAS Ctlg | rs568408 |
| GMAF | 0.1281 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19118071] rs568408(A) and rs3212227(C) variant genotypes were associated with a significantly increased risk of cervical cancer [adjusted odds ratio, 1.43; 95% confidence interval (CI), 1.06-1.93; and adjusted odds ratio, 1.30; 95% CI, 0.97-1.75, respectively]. subjects carrying variant genotypes of both loci had a 1.82-fold (95% CI, 1.28-2.57) increased risk of cervical cancer
[PMID 21513752] Association of single nucleotide polymorphisms in interleukin 12 (IL-12A and -B) with asthma in a Chinese population
[PMID 16449530
] Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.
[PMID 17327408] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
[PMID 18633131] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
[PMID 19066394] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
[PMID 20521253] IL12 polymorphisms, HBV infection and risk of hepatocellular carcinoma in a high-risk Chinese population.
[PMID 20544370] Association of genetic polymorphisms in the IL12-IFNG pathway with susceptibility to and prognosis of pulmonary tuberculosis in a Chinese population.
[PMID 20952689] Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma.
[PMID 21044109] Association study of interleukin-12A gene polymorphisms with Graves' disease in two Chinese populations.
[PMID 22515181] Interleukin-12: clinical usage and molecular markers of cancer susceptibility.
[PMID 22614250] Contribution of IL12A and IL12B Polymorphisms to the Risk of Cervical Cancer.
[PMID 22740240] Associations between polymorphisms in IL-12A, IL-12B, IL-12Rbeta1, IL-27 gene and serum levels of IL-12p40, IL-27p28 with esophageal cancer.
[PMID 22940148] Functional polymorphisms in the interleukin-12 gene contribute to cancer risk: evidence from a meta-analysis of 18 case-control studies.
[PMID 23065210] Interactions of interleukin-12A and interleukin-12B polymorphisms on the risk of intracranial aneurysm.
[PMID 25037175] Association of IL-12A and IL-12B polymorphisms with Alzheimer's disease susceptibility in a Han Chinese population
[PMID 26104769] Interaction analysis of IL-12A and IL-12B polymorphisms with the risk of colorectal cancer
[PMID 26631030] Genetic variants in IL12 influence both hepatitis B virus clearance and HBV-related hepatocellular carcinoma development in a Chinese male population.
[PMID 32602796] Association of Polymorphisms in Cytokine genes with susceptibility to Precancerous Lesions and Cervical Cancer: A systematic review with meta-analysis.
