rs6136
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common |
| (A;C) | None | |
| (C;C) | None | |
| (T;T) | 0 |
| Reference | GRCh38 38.1/142 |
| Chromosome | 1 |
| Position | 169594713 |
| Gene | SELP |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6136 |
| dbSNP (classic) | rs6136 |
| ClinGen | rs6136 |
| ebi | rs6136 |
| HLI | rs6136 |
| Exac | rs6136 |
| Gnomad | rs6136 |
| Varsome | rs6136 |
| LitVar | rs6136 |
| Map | rs6136 |
| PheGenI | rs6136 |
| Biobank | rs6136 |
| 1000 genomes | rs6136 |
| hgdp | rs6136 |
| ensembl | rs6136 |
| geneview | rs6136 |
| scholar | rs6136 |
| rs6136 | |
| pharmgkb | rs6136 |
| gwascentral | rs6136 |
| openSNP | rs6136 |
| 23andMe | rs6136 |
| SNPshot | rs6136 |
| SNPdbe | rs6136 |
| MSV3d | rs6136 |
| GWAS Ctlg | rs6136 |
| GMAF | 0.04408 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 17944986] cardiovascular risk
| GWAS snp | |
|---|---|
| PMID | [PMID 20167578 ]
|
| Trait | Soluble levels of adhesion molecules |
| Title | Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels |
| Risk Allele | T |
| P-val | 4E-61 |
| Odds Ratio | 22.60 [19.86-25.34] % increase |
[PMID 22473907] P-selectin genotype is associated with the development of cancer cachexia
| ClinVar | |
|---|---|
| Risk | Rs6136(C;C) |
| Alt | Rs6136(C;C) |
| Reference | Rs6136(A;A) |
| Significance | Non-pathogenic |
| Disease | SELECTIN P POLYMORPHISM |
| Variation | info |
| Gene | SELP |
| CLNDBN | SELECTIN P POLYMORPHISM |
| Reversed | 1 |
| HGVS | NC_000001.10:g.169563951T>G |
| CLNSRC | OMIM Allelic Variant |
| CLNACC | RCV000014482.2, |
[PMID 16820586] Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
[PMID 19404301] Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.
[PMID 24504449] SELP genetic polymorphisms may contribute to the pathogenesis of coronary heart disease and myocardial infarction: a meta-analysis
[PMID 25147926] Cellular Adhesion Gene SELP Is Associated with Rheumatoid Arthritis and Displays Differential Allelic Expression
[PMID 30047017] Association of SELP Polymorphisms with Soluble P-Selectin Levels and Vascular Risk in Patients with Type 2 Diabetes Mellitus: A Case-Control Study.
