rs6495308
| Orientation | plus |
| Stabilized | plus |
| Make rs6495308(C;C) |
| Make rs6495308(C;T) |
| Make rs6495308(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 78615314 |
| Gene | CHRNA3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6495308 |
| dbSNP (classic) | rs6495308 |
| ClinGen | rs6495308 |
| ebi | rs6495308 |
| HLI | rs6495308 |
| Exac | rs6495308 |
| Gnomad | rs6495308 |
| Varsome | rs6495308 |
| LitVar | rs6495308 |
| Map | rs6495308 |
| PheGenI | rs6495308 |
| Biobank | rs6495308 |
| 1000 genomes | rs6495308 |
| hgdp | rs6495308 |
| ensembl | rs6495308 |
| geneview | rs6495308 |
| scholar | rs6495308 |
| rs6495308 | |
| pharmgkb | rs6495308 |
| gwascentral | rs6495308 |
| openSNP | rs6495308 |
| 23andMe | rs6495308 |
| SNPshot | rs6495308 |
| SNPdbe | rs6495308 |
| MSV3d | rs6495308 |
| GWAS Ctlg | rs6495308 |
| GMAF | 0.4389 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 20418889
] Meta-analysis and imputation refines the association of 15q25 with smoking quantity
[PMID 18165968] Identification of pharmacogenetic markers in smoking cessation therapy.
[PMID 18227835] Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking.
[PMID 18519524] Variants in nicotinic receptors and risk for nicotine dependence.
[PMID 18571741] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.
[PMID 19259974] Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.
[PMID 19443489] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
[PMID 19706762] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
[PMID 20700436] Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
[PMID 20808433] Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.
[PMID 22223462] Alpha-5 and -3 nicotinic receptor gene variants predict nicotine dependence but not cessation: findings from the COMMIT cohort.
[PMID 25632390] Association between genetic variants on chromosome 15q25 locus and several nicotine dependence traits in Polish population: a case-control study
[PMID 30453884] Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence.
