rs660339
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in clinvar |
| Make rs660339(C;T) |
| Make rs660339(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 73978059 |
| Gene | UCP2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs660339 |
| dbSNP (classic) | rs660339 |
| ClinGen | rs660339 |
| ebi | rs660339 |
| HLI | rs660339 |
| Exac | rs660339 |
| Gnomad | rs660339 |
| Varsome | rs660339 |
| LitVar | rs660339 |
| Map | rs660339 |
| PheGenI | rs660339 |
| Biobank | rs660339 |
| 1000 genomes | rs660339 |
| hgdp | rs660339 |
| ensembl | rs660339 |
| geneview | rs660339 |
| scholar | rs660339 |
| rs660339 | |
| pharmgkb | rs660339 |
| gwascentral | rs660339 |
| openSNP | rs660339 |
| 23andMe | rs660339 |
| SNPshot | rs660339 |
| SNPdbe | rs660339 |
| MSV3d | rs660339 |
| GWAS Ctlg | rs660339 |
| GMAF | 0.4316 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19833146] Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain
[PMID 17066476] Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia.
[PMID 17601350
] A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
[PMID 17894153] Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding.
[PMID 18496642] Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study.
[PMID 18599530] Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.
[PMID 18956255] Human uncoupling protein 2 and 3 genes are associated with obesity in Japanese.
[PMID 18996102] Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.
[PMID 19681913] Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.
[PMID 19760975] Prediction of successful weight reduction after laparoscopic adjustable gastric banding.
[PMID 19769793] Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study.
[PMID 20142250] Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.
[PMID 21720911] ESR1, FTO, and UCP2 genes interact with bariatric surgery affecting weight loss and glycemic control in severely obese patients.
[PMID 21883184] Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population.
[PMID 22533685] Uncoupling protein 2 gene polymorphisms are associated with obesity
[PMID 23681449] Genes for Elite Power and Sprint Performance: ACTN3 Leads the Way
[PMID 25396419] Investigation of Variants in UCP2 in Chinese Type 2 Diabetes and Diabetic Retinopathy
| ClinVar | |
|---|---|
| Risk | rs660339(T;T) |
| Alt | rs660339(T;T) |
| Reference | Rs660339(C;C) |
| Significance | Other |
| Disease | not specified |
| Variation | info |
| Gene | UCP2 |
| CLNDBN | not specified |
| Reversed | 1 |
| HGVS | NC_000011.9:g.73689104G>A |
| CLNSRC | UniProtKB (protein) |
| CLNACC | RCV000118811.3, |
[PMID 27615599] Interactions between UCP2 SNPs and telomere length exist in the absence of diabetes or pre-diabetes.
[PMID 30204480] Machine Learning-Based Method for Obesity Risk Evaluation Using Single-Nucleotide Polymorphisms Derived from Next-Generation Sequencing.
